Citrobacter koseri strain NCTC11075

Citrobacter koseri strain NCTC11075 is a Gram-negative, facultatively anaerobic bacterium characterized by its rod shape and motility, facilitated by the presence of flagella. This strain thrives in a mesophilic temperature range, indicating an optimal growth temperature typically between 20°C and 45°C. As a free-living organism, C. koseri can inhabit various environments, including those associated with its hosts, which include Homo sapiens and Rodentia. This bacterium is known for its pathogenic effects in humans, where it is implicated in several serious health conditions such as brain abscesses, meningitis, sepsis, urinary tract infections (UTIs), and infective aortic endocarditis. Notably, it is associated with both community-acquired and catheter-associated urinary tract infections (CAUTI), demonstrating its potential to cause significant clinical issues. The presence of a single replicon and two membranes is consistent with the general structure of Gram-negative bacteria, which feature an outer membrane that plays a role in their pathogenicity and resistance to certain antibiotics. The association of C. koseri with severe infections highlights its role in human health and disease, particularly in immunocompromised individuals or those with underlying health conditions. Understanding the ecological niches of C. koseri, along with its pathogenic potential, underscores the importance of monitoring this bacterium in both clinical and environmental settings.