Alistipes finegoldii DSM 17242

Alistipes finegoldii DSM 17242 is classified as a mesophile, a chemoheterotrophic organism that produces energy through fermentation, is Gram-negative, rod-shaped, predominantly resides in the human gut, and is an obligate anaerobe. This bacterium thrives at moderate temperatures, ideally between 20°C and 45°C, which aligns with the human body temperature, making it well-suited for its ecological niche. As a chemoheterotroph, A. finegoldii relies on organic compounds from its environment for energy, engaging in fermentation processes to generate adenosine triphosphate (ATP). The Gram-negative nature of A. finegoldii is indicative of its cell wall structure, which contains a thin peptidoglycan layer surrounded by an outer membrane rich in lipopolysaccharides. This feature not only influences its pathogenic potential but also its interaction with the host immune system. The rod shape of the microbe aids in its motility within the dense microbial community of the gut, enabling effective colonization and nutrient acquisition. Predominantly found in the human gastrointestinal tract, A. finegoldii plays a pivotal role in maintaining gut health and homeostasis. Its obligate anaerobic lifestyle means it thrives in environments devoid of oxygen, which is characteristic of the human intestine, where it interacts with other gut microbiota to contribute to digestion and metabolic processes. Recent studies have indicated that A. finegoldii may be involved in the metabolism of certain dietary components, potentially influencing host metabolism and immune responses. Furthermore, its presence or absence has been linked to various health conditions, suggesting a role in maintaining the balance of the gut microbiome. Ongoing research into A. finegoldii may reveal more about its contributions to human health and disease, underscoring its importance in the field of microbiology and gut health research.