Citrobacter koseri strain NCTC10810

Gram-negativeRodMotileFacultatively anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Citrobacter

Description

Citrobacter koseri strain NCTC10810 is a Gram-negative, rod-shaped bacterium that falls under the category of facultatively anaerobes, indicating its ability to thrive in both aerobic and anaerobic environments. This strain is mesophilic, meaning it grows optimally within a moderate temperature range. It possesses flagella, allowing for mobility, and has a unique cellular architecture characterized by two membranes and a single replicon. C. koseri is notably free-living but has significant pathogenic potential in humans and rodents, acting as an opportunistic pathogen. It is associated with various serious health complications, including brain abscesses, meningitis, and sepsis. Moreover, it is implicated in urinary tract infections, specifically catheter-associated urinary tract infections (CAUTI) and community-acquired UTIs, as well as infective aortic endocarditis. The bacterium's ability to cause multiple brain abscesses further highlights its pathogenicity. Ecologically, the presence of C. koseri in both human and rodent hosts suggests a versatile adaptability, allowing it to thrive in diverse environments. Its pathogenic capabilities in humans, particularly in immunocompromised individuals or those with underlying health conditions, underscore its role as a significant concern in clinical microbiology. Understanding the traits of Citrobacter koseri NCTC10810 can aid in developing strategies for prevention and treatment of the infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusCitrobacter
SpeciesCitrobacter koseri
Strainstrain NCTC10810

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Citrobacter koseri strain NCTC10810
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultatively anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Rodentia
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Citrobacter koseri strain NCTC10810 genome assembly, contig:

Gene Summary

Adenine Count

1091542 bp

Thymine Count

1095790 bp

Guanine Count

1274669 bp

Cytosine Count

1270729 bp

Genome Length

4732730 bp

Protein-coding Genes

5280 genes

Non-Coding Genes

155 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
outer membrane protein n, non-specific porinNCTC10810_05051Not AvailablePositive4256515 - 425755239107.9
uncharacterised proteinNCTC10810_05052Not AvailablePositive4257563 - 425833928576.0
uncharacterised proteinNCTC10810_05053Not AvailableNegative4258376 - 42584924131.05
tonb dependent receptorNCTC10810_05054Not AvailableNegative4258523 - 426073080561.7
dna-binding transcriptional regulator galsNCTC10810_05055Not AvailablePositive4261087 - 426213938158.5
5s ribosomal rnaNot AvailableNot AvailablePositive4261500 - 4261614Not Available
23s ribosomal rnaNot AvailableNot AvailablePositive4261712 - 4264614Not Available
fuscose transport/metabolism proteinNCTC10810_05056Not AvailableNegative4262178 - 426259715352.7
dehydrogenaseNCTC10810_05057Not AvailableNegative4262643 - 426305914283.0
short-chain dehydrogenaseNCTC10810_05058Not AvailableNegative4263067 - 426340812177.6

Displaying genes 4931 – 4940 of 5435 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC13268207
Community-acquired utisCausesPMC13268207
Infective aortic endocarditisCausesPMC2786675
Brain abscessesCausesPMC2833190
Catheter-associated urinary tract infectionCausesPMC2900259
CautiCausesPMC2900259
Central nervous system infectionsCausesPMC4793686
SepsisCausesPMC4793686
MeningitisCausesPMC4793686
Multiple brain abscessesCausesPMC4793686

Displaying health effects 1 – 10 of 10 in total