Citrobacter koseri strain NCTC10810

Gram-negativeRodMotileFacultatively anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Citrobacter

Description

Citrobacter koseri strain NCTC10810 is a Gram-negative, rod-shaped bacterium that falls under the category of facultatively anaerobes, indicating its ability to thrive in both aerobic and anaerobic environments. This strain is mesophilic, meaning it grows optimally within a moderate temperature range. It possesses flagella, allowing for mobility, and has a unique cellular architecture characterized by two membranes and a single replicon. C. koseri is notably free-living but has significant pathogenic potential in humans and rodents, acting as an opportunistic pathogen. It is associated with various serious health complications, including brain abscesses, meningitis, and sepsis. Moreover, it is implicated in urinary tract infections, specifically catheter-associated urinary tract infections (CAUTI) and community-acquired UTIs, as well as infective aortic endocarditis. The bacterium's ability to cause multiple brain abscesses further highlights its pathogenicity. Ecologically, the presence of C. koseri in both human and rodent hosts suggests a versatile adaptability, allowing it to thrive in diverse environments. Its pathogenic capabilities in humans, particularly in immunocompromised individuals or those with underlying health conditions, underscore its role as a significant concern in clinical microbiology. Understanding the traits of Citrobacter koseri NCTC10810 can aid in developing strategies for prevention and treatment of the infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusCitrobacter
SpeciesCitrobacter koseri
Strainstrain NCTC10810

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Citrobacter koseri strain NCTC10810
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultatively anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Rodentia
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Citrobacter koseri strain NCTC10810 genome assembly, contig:

Gene Summary

Adenine Count

1091542 bp

Thymine Count

1095790 bp

Guanine Count

1274669 bp

Cytosine Count

1270729 bp

Genome Length

4732730 bp

Protein-coding Genes

5280 genes

Non-Coding Genes

155 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hflk proteinNCTC10810_04135Not AvailablePositive3457669 - 345817218527.1
uncharacterised proteinNCTC10810_04136Not AvailablePositive3458181 - 345858514543.2
inner membrane protein ybbjNCTC10810_04137Not AvailablePositive3458582 - 345903416568.6
dna-binding transcriptional regulator cuerNCTC10810_04138Not AvailableNegative3459035 - 345937612773.2
ferrienterobactin tonb-dependent receptor (enterobactin outer-membrane receptor)NCTC10810_04139Not AvailablePositive3459955 - 346113343512.1
outer membrane cobalamin receptor proteinNCTC10810_04140Not AvailablePositive3461280 - 346186421717.2
vitamin b12-binding proteinNCTC10810_04141Not AvailablePositive3462001 - 346262121929.4
coproporphyrinogen iii oxidaseNCTC10810_04142Not AvailablePositive3462790 - 346312512597.1
coproporphyrinogen iii oxidaseNCTC10810_04143Not AvailablePositive3463122 - 34633166978.43
coproporphyrinogen iii oxidaseNCTC10810_04144Not AvailablePositive3463313 - 34634143739.82

Displaying genes 4051 – 4060 of 5435 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC13268207
Community-acquired utisCausesPMC13268207
Infective aortic endocarditisCausesPMC2786675
Brain abscessesCausesPMC2833190
Catheter-associated urinary tract infectionCausesPMC2900259
CautiCausesPMC2900259
Central nervous system infectionsCausesPMC4793686
SepsisCausesPMC4793686
MeningitisCausesPMC4793686
Multiple brain abscessesCausesPMC4793686

Displaying health effects 1 – 10 of 10 in total