Citrobacter koseri strain NCTC10786

Gram-negativeRodMotileFacultatively anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Citrobacter

Description

Citrobacter koseri strain NCTC10786 is a Gram-negative, facultatively anaerobic bacterium characterized by its rod shape. This strain is motile, possessing flagella that enable movement. It is classified as mesophilic, indicating that it thrives in moderate temperature ranges. C. koseri has a unique cellular structure with two membranes and contains a single replicon. This organism is free-living and can inhabit multiple environments, making it versatile in its ecological niches. It has been identified as a pathogen in humans, associated with several serious health issues, including brain abscesses, meningitis, sepsis, urinary tract infections (UTIs), and infective aortic endocarditis. Specifically, it has been linked to community-acquired UTIs and catheter-associated urinary tract infections (CAUTI). Additionally, it can infect rodent hosts, further demonstrating its pathogenic potential across different species. The health impacts of C. koseri highlight its significance in clinical microbiology, particularly in immunocompromised patients or those with underlying health conditions. Its ability to cause central nervous system infections and other severe conditions underscores the necessity for continued research and monitoring of this organism in healthcare settings. Understanding the ecological role and pathogenicity of Citrobacter koseri can provide insights into its transmission dynamics and potential control measures in both human health and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusCitrobacter
SpeciesCitrobacter koseri
Strainstrain NCTC10786

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Citrobacter koseri strain NCTC10786
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultatively anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Rodentia
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Citrobacter koseri strain NCTC10786 genome assembly, contig:

Gene Summary

Adenine Count

1071342 bp

Thymine Count

1082002 bp

Guanine Count

1266285 bp

Cytosine Count

1241829 bp

Genome Length

4661458 bp

Protein-coding Genes

6321 genes

Non-Coding Genes

197 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative multidrug transporter membrane-atp-binding componentsNCTC10786_00839Not AvailableNegative590123 - 59109735516.3
putative multidrug transporter membrane-atp-binding componentsNCTC10786_00840Not AvailableNegative591087 - 59190229577.6
abc transporter atp-binding protein/permeaseNCTC10786_00841Not AvailableNegative591895 - 59366766114.5
transcriptional regulatorNCTC10786_00842Not AvailableNegative593712 - 59417017420.3
lyaseNCTC10786_00843Not AvailablePositive594283 - 59533839169.4
hydrolaseNCTC10786_00844Not AvailableNegative595392 - 5956679893.07
hydrolaseNCTC10786_00845Not AvailableNegative595648 - 59621120828.2
substrate-binding proteinNCTC10786_00846Not AvailablePositive596312 - 59761649474.0
substrate-binding proteinNCTC10786_00847Not AvailablePositive597687 - 59804913583.0
queuosine biosynthesis protein quecNCTC10786_00848Not AvailablePositive598077 - 59877225419.4

Displaying genes 971 – 980 of 6518 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC13268207
Community-acquired utisCausesPMC13268207
Infective aortic endocarditisCausesPMC2786675
Brain abscessesCausesPMC2833190
Catheter-associated urinary tract infectionCausesPMC2900259
CautiCausesPMC2900259
Central nervous system infectionsCausesPMC4793686
SepsisCausesPMC4793686
MeningitisCausesPMC4793686
Multiple brain abscessesCausesPMC4793686

Displaying health effects 1 – 10 of 10 in total