Citrobacter freundii strain NCTC13639

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Citrobacter

Description

Citrobacter freundii strain NCTC13639 is a Gram-negative, rod-shaped bacterium that thrives in various habitats, including hospital sewage, the intestinal tract, sewage, soil, and surface waters. It is classified as a facultative anaerobe, indicating its ability to grow in both aerobic and anaerobic environments, and possesses true flagella, which facilitate its motility. This strain has a single replicon and is known to infect a diverse array of hosts, including humans (Homo sapiens), various animals such as rabbits (Oryctolagus cuniculus), tilapia, domestic dogs (Canis lupus familiaris), and cats (Felis catus), as well as amphibians and fish. The bacterium is recognized for being an opportunistic pathogen, responsible for infections in humans and animals, particularly affecting the urinary and respiratory tracts. In horses, it can lead to respiratory tract and wound infections, while in dogs and cats, it is associated with respiratory tract infections and pleuritis. C. freundii strain NCTC13639 is nonsporulating, which may influence its ecological persistence and pathogenicity. The wide range of hosts and environments it occupies suggests a significant role in both clinical settings and natural ecosystems. The bacterium's presence in hospital sewage underlines its relevance in healthcare, where it can pose infection risks, particularly in immunocompromised patients. Understanding its ecological niche and pathogenic potential is essential for managing infections and preventing outbreaks in both humans and animals.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusCitrobacter
SpeciesCitrobacter freundii
Strainstrain NCTC13639

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Image of Citrobacter freundii strain NCTC13639
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitathospital sewage; intestinal tract; sewage; soil; surface waters
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Oryctolagus cuniculus
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Citrobacter freundii strain NCTC13639 genome assembly, contig:

Gene Summary

Adenine Count

1365926 bp

Thymine Count

1362255 bp

Guanine Count

1468521 bp

Cytosine Count

1463287 bp

Genome Length

5659989 bp

Protein-coding Genes

5404 genes

Non-Coding Genes

644 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fimbrial usher proteinNCTC13639_04614Not AvailableNegative4260661 - 426313291268.4
fimbrial subunitNCTC13639_04615Not AvailableNegative4263174 - 426372220159.8
major fimbrial subunitNCTC13639_04616Not AvailableNegative4263792 - 426434018836.0
transcriptional regulatorNCTC13639_04617Not AvailablePositive4264986 - 426577429378.7
uncharacterised proteinNCTC13639_04618Not AvailablePositive4265776 - 426629419326.1
Trna-aspNot AvailableNot AvailablePositive4266452 - 4266528Not Available
dna polymerase iii subunit epsilonNCTC13639_04620Not AvailableNegative4266663 - 426740027481.9
ribonuclease hNCTC13639_04621Not AvailablePositive4267456 - 426792317575.9
biotin biosynthesis protein biocNCTC13639_04622Not AvailableNegative4267920 - 426864227305.5
hydroxyacylglutathione hydrolaseNCTC13639_04623Not AvailablePositive4268676 - 426943128620.3

Displaying genes 4731 – 4740 of 6048 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Infections in animalsCausesPMC6885840
Infections of the urinary and respiratory tracts in humansCausesPMC6885840
Respiratory tract and wound infections in horsesCausesPMC6885840
Respiratory tract infections in dogsCausesPMC6885840
Pleuritis and urinary tract infections in catsCausesPMC6885840
Bacterial infectionsCausesPMC7578172
Opportunistic infectionsCausesPMC12838003

Displaying health effects 1 – 7 of 7 in total