Citrobacter freundii strain NCTC13639

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Citrobacter

Description

Citrobacter freundii strain NCTC13639 is a Gram-negative, rod-shaped bacterium that thrives in various habitats, including hospital sewage, the intestinal tract, sewage, soil, and surface waters. It is classified as a facultative anaerobe, indicating its ability to grow in both aerobic and anaerobic environments, and possesses true flagella, which facilitate its motility. This strain has a single replicon and is known to infect a diverse array of hosts, including humans (Homo sapiens), various animals such as rabbits (Oryctolagus cuniculus), tilapia, domestic dogs (Canis lupus familiaris), and cats (Felis catus), as well as amphibians and fish. The bacterium is recognized for being an opportunistic pathogen, responsible for infections in humans and animals, particularly affecting the urinary and respiratory tracts. In horses, it can lead to respiratory tract and wound infections, while in dogs and cats, it is associated with respiratory tract infections and pleuritis. C. freundii strain NCTC13639 is nonsporulating, which may influence its ecological persistence and pathogenicity. The wide range of hosts and environments it occupies suggests a significant role in both clinical settings and natural ecosystems. The bacterium's presence in hospital sewage underlines its relevance in healthcare, where it can pose infection risks, particularly in immunocompromised patients. Understanding its ecological niche and pathogenic potential is essential for managing infections and preventing outbreaks in both humans and animals.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusCitrobacter
SpeciesCitrobacter freundii
Strainstrain NCTC13639

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Image of Citrobacter freundii strain NCTC13639
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitathospital sewage; intestinal tract; sewage; soil; surface waters
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Oryctolagus cuniculus
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Citrobacter freundii strain NCTC13639 genome assembly, contig:

Gene Summary

Adenine Count

1365926 bp

Thymine Count

1362255 bp

Guanine Count

1468521 bp

Cytosine Count

1463287 bp

Genome Length

5659989 bp

Protein-coding Genes

5404 genes

Non-Coding Genes

644 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinNCTC13639_02546Not AvailableNegative2338435 - 23386748384.55
phopq regulatory proteinNCTC13639_02547Not AvailablePositive2338839 - 23389825560.21
uncharacterised proteinNCTC13639_02548Not AvailablePositive2339057 - 233934110401.5
penicillin-binding proteinNCTC13639_02550Not AvailablePositive2340563 - 234230863062.8
23s rrna methyltransferase aNCTC13639_02551Not AvailablePositive2342372 - 234318129891.8
putative sporulation protein ytafNCTC13639_02552Not AvailableNegative2343178 - 234374420131.3
predicted membrane proteinNCTC13639_02553Not AvailableNegative2344176 - 234463417853.5
mannose-specific pts system eiid componentNCTC13639_02554Not AvailableNegative2344695 - 234554630872.4
mannose-specific pts system eiic componentNCTC13639_02555Not AvailableNegative2345559 - 234635927510.4
mannose-specific pts system eiiab componentNCTC13639_02556Not AvailableNegative2346418 - 234738034802.2

Displaying genes 2841 – 2850 of 6048 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Infections in animalsCausesPMC6885840
Infections of the urinary and respiratory tracts in humansCausesPMC6885840
Respiratory tract and wound infections in horsesCausesPMC6885840
Respiratory tract infections in dogsCausesPMC6885840
Pleuritis and urinary tract infections in catsCausesPMC6885840
Bacterial infectionsCausesPMC7578172
Opportunistic infectionsCausesPMC12838003

Displaying health effects 1 – 7 of 7 in total