Shigella flexneri 4c strain 1205

Gram-negativeRodMotileFacultative

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Shigella

Description

Shigella flexneri 4c strain 1205 is a pathogenic, Gram-negative bacterium known for its role in causing severe gastrointestinal diseases in humans and other primates. This organism is a rod-shaped, facultative anaerobe that typically thrives at an optimal temperature of 37°C, making it mesophilic. The bacterium exhibits mobility, facilitated by the presence of flagella, and it typically exists in pairs or singles within its habitat, which is primarily associated with hosts such as Homo sapiens and certain primates. S. flexneri 4c strain 1205 is classified as a chemoorganotroph, obtaining energy from organic compounds. It has a complex cellular structure comprising two membranes and four replicons, which are indicative of its genetic organization. This strain does not form spores and is free-living in its environment. The health impacts of this strain are significant, as it is associated with various forms of dysentery, including shigellosis and bacillary dysentery. These infections can lead to severe diarrhea, posing a considerable public health challenge, especially in areas with inadequate sanitation. Ecologically, the presence of S. flexneri 4c strain 1205 highlights the intricate relationships between pathogenic bacteria and their hosts. As a free-living organism that can cause disease, it underscores the importance of understanding microbial dynamics in human and primate populations, particularly in the context of disease transmission and outbreaks. The ability of this strain to adapt to its hosts and environmental conditions reflects the ongoing evolutionary interactions within microbial communities.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusShigella
SpeciesShigella flexneri
Strain4c strain 1205

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Shigella flexneri 4c strain 1205
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Primates, Pteropodidae
Cell arrangementPairs-Singles
SporulationNonsporulating
Energy source Chemoorganotroph
PathogenicityHuman

Genome Summary

Shigella flexneri 4c strain 1205


Gene Summary

Adenine Count

59349 bp

Thymine Count

60879 bp

Guanine Count

52267 bp

Cytosine Count

49565 bp

Genome Length

222060 bp

Protein-coding Genes

270 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Gp245AD871_RS05310Not AvailablePositive1000211 - 100113734361.6
glycine betaine abc transporter permease yehwAD871_RS05315Not AvailablePositive1001142 - 100187325598.3
protein yohoAD871_RS05320Not AvailableNegative1001854 - 10019613642.85
transcriptional regulatorAD871_RS05325Not AvailableNegative1002021 - 100247717082.8
Transposase orfa protein of insertion sequence is629AD871_RS28485Not AvailableNegative1002519 - 100372843045.7
merr family transcriptional regulatorAD871_RS05345Not AvailableNegative1003784 - 10040359881.91
Putative integraseAD871_RS05350Not AvailableNegative1004056 - 100441213563.2
Transposase is1AD871_RS05355Not AvailableNegative1004427 - 100512426529.3
Tail fiber proteinAD871_RS05365Not AvailablePositive1005157 - 100557915624.2
Putative tail fiber assembly proteinAD871_RS05370Not AvailablePositive1005582 - 100612720696.2

Displaying genes 491 – 500 of 5400 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
ShigellosisCausesPMC2600399
ShigellosisCausesPMC5109407
ShigellosisCausesPMC5177732
Severe diarrheaCausesPMC8742002
Dysenteric diseaseCausesPMC8742002
ShigellosisCausesPMC8742002
Bacillary dysenteryCausesPMC8742002
Pandemic dysenteryCausesPMC8742002
Bacillary dysenteryCausesPMC4159516
ShigellosisCausesPMC5429569

Displaying health effects 1 – 10 of 10 in total