Shigella flexneri 4c strain 1205

Gram-negativeRodMotileFacultative

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Shigella

Description

Shigella flexneri 4c strain 1205 is a pathogenic, Gram-negative bacterium known for its role in causing severe gastrointestinal diseases in humans and other primates. This organism is a rod-shaped, facultative anaerobe that typically thrives at an optimal temperature of 37°C, making it mesophilic. The bacterium exhibits mobility, facilitated by the presence of flagella, and it typically exists in pairs or singles within its habitat, which is primarily associated with hosts such as Homo sapiens and certain primates. S. flexneri 4c strain 1205 is classified as a chemoorganotroph, obtaining energy from organic compounds. It has a complex cellular structure comprising two membranes and four replicons, which are indicative of its genetic organization. This strain does not form spores and is free-living in its environment. The health impacts of this strain are significant, as it is associated with various forms of dysentery, including shigellosis and bacillary dysentery. These infections can lead to severe diarrhea, posing a considerable public health challenge, especially in areas with inadequate sanitation. Ecologically, the presence of S. flexneri 4c strain 1205 highlights the intricate relationships between pathogenic bacteria and their hosts. As a free-living organism that can cause disease, it underscores the importance of understanding microbial dynamics in human and primate populations, particularly in the context of disease transmission and outbreaks. The ability of this strain to adapt to its hosts and environmental conditions reflects the ongoing evolutionary interactions within microbial communities.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusShigella
SpeciesShigella flexneri
Strain4c strain 1205

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Shigella flexneri 4c strain 1205
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Primates, Pteropodidae
Cell arrangementPairs-Singles
SporulationNonsporulating
Energy source Chemoorganotroph
PathogenicityHuman

Genome Summary

Shigella flexneri 4c strain 1205 plasmid 1205p2, complete

Gene Summary

Adenine Count

59349 bp

Thymine Count

60879 bp

Guanine Count

52267 bp

Cytosine Count

49565 bp

Genome Length

222060 bp

Protein-coding Genes

270 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
inosine/xanthosine triphosphataseAD871_RS13540Not AvailableNegative2440207 - 244066816341.5
nicotinamide mononucleotide deamidase-related protein yfayAD871_RS13545Not AvailableNegative2440732 - 244193444268.3
yfaz family outer membrane proteinAD871_RS13550Not AvailableNegative2442021 - 244256318612.8
nucleoside triphosphatase nudiAD871_RS13555Not AvailablePositive2442842 - 244326716361.6
lipopolysaccharide core heptose(ii)-phosphate phosphatase aisAD871_RS13560Not AvailableNegative2443306 - 244390822292.8
udp-4-amino-4-deoxy-l-arabinose aminotransferaseAD871_RS13565Not AvailablePositive2444216 - 244535541672.2
undecaprenyl-phosphate 4-deoxy-4-formamido-l-arabinose transferaseAD871_RS13570Not AvailablePositive2445359 - 244632736341.3
inosine/xanthosine triphosphataseAD871_RS13575Not AvailablePositive2446327 - 244830872305.3
4-deoxy-4-formamido-l-arabinose- phosphoundecaprenol deformylaseAD871_RS13580Not AvailablePositive2448305 - 244919533065.6
lipid iv(a) 4-amino-4-deoxy-l-arabinosyltransferaseAD871_RS13585Not AvailablePositive2449195 - 245084762526.9

Displaying genes 2921 – 2930 of 5400 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
ShigellosisCausesPMC2600399
ShigellosisCausesPMC5109407
ShigellosisCausesPMC5177732
Severe diarrheaCausesPMC8742002
Dysenteric diseaseCausesPMC8742002
ShigellosisCausesPMC8742002
Bacillary dysenteryCausesPMC8742002
Pandemic dysenteryCausesPMC8742002
Bacillary dysenteryCausesPMC4159516
ShigellosisCausesPMC5429569

Displaying health effects 1 – 10 of 10 in total