Vibrio cholerae strain TSY216

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Vibrionales

Family

Vibrionaceae

Genus

Vibrio

Description

Vibrio cholerae strain TSY216 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It is a heterotroph, deriving its energy from organic compounds, and it exists primarily in a free-living state. The strain exhibits motility due to the presence of flagella, although it is noted as non-motile in certain contexts. TSY216 has an optimal growth temperature of 20°C, placing it within the mesophilic temperature range, which is conducive to its survival in various habitats. This strain possesses three replicons and has a unique structure characterized by two membranes. Its biotic relationships extend to multiple hosts, including humans (Homo sapiens), mollusks, mammals, and shrimp (Penaeus vannamei). TSY216 is known to be pathogenic to humans, contributing to a wide array of health issues ranging from gastrointestinal infections, such as cholera and gastroenteritis, to more severe conditions like pneumonia, sepsis, and necrotizing fasciitis. The ecological implications of Vibrio cholerae strain TSY216 highlight its role in aquatic environments, particularly in relation to its interactions with marine and freshwater organisms. Its ability to cause illness in humans, particularly through water sources, underscores the importance of monitoring environmental conditions that favor its proliferation. The strain's pathogenicity, coupled with its diverse host range, illustrates the complex dynamics of microbial life and its impact on public health and ecosystem balance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderVibrionales
FamilyVibrionaceae
GenusVibrio
SpeciesVibrio cholerae
Strainstrain TSY216

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Vibrio cholerae strain TSY216
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature20
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Mollusca, Mammalia
Cell arrangementSingles
SporulationNonsporulating
Energy sourceHeterotroph
PathogenicityHuman

Genome Summary

Vibrio cholerae strain TSY216 chromosome 2, complete sequence.

Gene Summary

Adenine Count

278172 bp

Thymine Count

278933 bp

Guanine Count

248510 bp

Cytosine Count

245669 bp

Genome Length

1051284 bp

Protein-coding Genes

992 genes

Non-Coding Genes

4 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glycogen/starch/alpha-glucan phosphorylaseEN12_RS14225P00490Positive11883 - 1433692570.8
4-alpha-glucanotransferaseEN12_RS14230P15977Positive14422 - 1660281385.6
1,4-alpha-glucan branching protein glgbEN12_RS14235Q9KNE8Positive16808 - 1899784031.0
type vi secretion system effector hcp-2EN12_RS14240Q9HI36Positive19392 - 1991019060.3
type vi secretion system vgr family proteinEN12_RS14245Q9KNE7Positive20038 - 2209876374.7
type vi secretion system accessory protein vaswEN12_RS14250Q9KNE6Positive22098 - 2298534215.6
type vi secretion system toxin vasxEN12_RS14255Q9KNE5Positive22982 - 26239121049.0
type vi secretion system immunity protein tsiv2EN12_RS14260Q9KNE4Positive26240 - 2696827882.4
mapeg family proteinEN12_RS14265P64515Positive27071 - 2747214880.7
acyltransferaseEN12_RS14270Q9X3P3Negative27645 - 2867038927.7

Displaying genes 11 – 20 of 4898 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

187 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000719chloramphenicol 3-acetateC13H14Cl2N2O6Chemical structure of chloramphenicol 3-acetateNot available
Average365.16Da
Monoisotopic364.0228916Da
BASm0000976enol-oxaloacetateC4H2O5Chemical structure of enol-oxaloacetateNot available
Average130.056Da
Monoisotopic129.9913203Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 187 metabolites

Health Effects

Health ConditionRelationReference
CholeraCausesPMC10103850
Ear infectionsCausesPMC10103850
Wound infectionsCausesPMC10103850
SepticaemiaCausesPMC10103850
Gastrointestinal infectionsCausesPMC10103850
Necrotizing fasciitisCausesPMC10103850
VibriosisCausesPMC10472736
PneumoniaCausesPMC12801787
GastroenteritisCausesPMC12801787
SinusitisCausesPMC12801787

Displaying health effects 1 – 10 of 38 in total