Vibrio cholerae strain TSY216

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Vibrionales

Family

Vibrionaceae

Genus

Vibrio

Description

Vibrio cholerae strain TSY216 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It is a heterotroph, deriving its energy from organic compounds, and it exists primarily in a free-living state. The strain exhibits motility due to the presence of flagella, although it is noted as non-motile in certain contexts. TSY216 has an optimal growth temperature of 20°C, placing it within the mesophilic temperature range, which is conducive to its survival in various habitats. This strain possesses three replicons and has a unique structure characterized by two membranes. Its biotic relationships extend to multiple hosts, including humans (Homo sapiens), mollusks, mammals, and shrimp (Penaeus vannamei). TSY216 is known to be pathogenic to humans, contributing to a wide array of health issues ranging from gastrointestinal infections, such as cholera and gastroenteritis, to more severe conditions like pneumonia, sepsis, and necrotizing fasciitis. The ecological implications of Vibrio cholerae strain TSY216 highlight its role in aquatic environments, particularly in relation to its interactions with marine and freshwater organisms. Its ability to cause illness in humans, particularly through water sources, underscores the importance of monitoring environmental conditions that favor its proliferation. The strain's pathogenicity, coupled with its diverse host range, illustrates the complex dynamics of microbial life and its impact on public health and ecosystem balance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderVibrionales
FamilyVibrionaceae
GenusVibrio
SpeciesVibrio cholerae
Strainstrain TSY216

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Vibrio cholerae strain TSY216
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature20
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Mollusca, Mammalia
Cell arrangementSingles
SporulationNonsporulating
Energy sourceHeterotroph
PathogenicityHuman

Genome Summary

Vibrio cholerae strain TSY216 chromosome 3, complete sequence.

Gene Summary

Adenine Count

284676 bp

Thymine Count

277531 bp

Guanine Count

161986 bp

Cytosine Count

171813 bp

Genome Length

896006 bp

Protein-coding Genes

1004 genes

Non-Coding Genes

67 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
replication initiator protein rctb domain-containing proteinEN12_RS14175Not AvailablePositive746 - 272275282.5
hypothetical proteinEN12_RS14180Not AvailableNegative2942 - 340317775.1
pa3496 family putative envelope integrity proteinEN12_RS14185Not AvailablePositive3766 - 39637533.86
duf3283 family proteinEN12_RS14190Not AvailablePositive4126 - 43357946.66
yebc/pmpr family dna-binding transcriptional regulatorEN12_RS14195A5F1N4Positive4423 - 514226355.0
nad(p)-dependent oxidoreductaseEN12_RS14200O33730Positive5257 - 613230599.2
methyl-accepting chemotaxis proteinEN12_RS14205Q9I0I6Negative6236 - 789760875.3
hypothetical proteinEN12_RS14210Not AvailablePositive7900 - 80947148.67
yibl family ribosome-associated proteinEN12_RS14215P0ADL0Positive8175 - 853113424.5
hth-type transcriptional regulator maltEN12_RS14220Q9KNF3Negative8598 - 11306103595.0

Displaying genes 1 – 10 of 4898 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

12 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm0003346(2R)-2-phosphoglycerateC3H4O7PChemical structure of (2R)-2-phosphoglycerateNot available
Average183.033Da
Monoisotopic182.9711102Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0004102dATPC10H12N5O12P3Chemical structure of dATP1927-31-7
Average487.152Da
Monoisotopic486.97172616Da
BASm0006041alpha-NAD(+)C21H26N7O14P2Chemical structure of alpha-NAD(+)Not available
Average662.422Da
Monoisotopic662.1018461Da
BASm00077082''-O-glutaryl-ADP-D-riboseC20H26N5O17P2Chemical structure of 2''-O-glutaryl-ADP-D-riboseNot available
Average670.395Da
Monoisotopic670.081539133Da

Displaying 1–10 of 12 metabolites

Health Effects

Health ConditionRelationReference
CholeraCausesPMC10103850
Ear infectionsCausesPMC10103850
Wound infectionsCausesPMC10103850
SepticaemiaCausesPMC10103850
Gastrointestinal infectionsCausesPMC10103850
Necrotizing fasciitisCausesPMC10103850
VibriosisCausesPMC10472736
PneumoniaCausesPMC12801787
GastroenteritisCausesPMC12801787
SinusitisCausesPMC12801787

Displaying health effects 1 – 10 of 38 in total