Vibrio cholerae strain TSY216

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Vibrionales

Family

Vibrionaceae

Genus

Vibrio

Description

Vibrio cholerae strain TSY216 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It is a heterotroph, deriving its energy from organic compounds, and it exists primarily in a free-living state. The strain exhibits motility due to the presence of flagella, although it is noted as non-motile in certain contexts. TSY216 has an optimal growth temperature of 20°C, placing it within the mesophilic temperature range, which is conducive to its survival in various habitats. This strain possesses three replicons and has a unique structure characterized by two membranes. Its biotic relationships extend to multiple hosts, including humans (Homo sapiens), mollusks, mammals, and shrimp (Penaeus vannamei). TSY216 is known to be pathogenic to humans, contributing to a wide array of health issues ranging from gastrointestinal infections, such as cholera and gastroenteritis, to more severe conditions like pneumonia, sepsis, and necrotizing fasciitis. The ecological implications of Vibrio cholerae strain TSY216 highlight its role in aquatic environments, particularly in relation to its interactions with marine and freshwater organisms. Its ability to cause illness in humans, particularly through water sources, underscores the importance of monitoring environmental conditions that favor its proliferation. The strain's pathogenicity, coupled with its diverse host range, illustrates the complex dynamics of microbial life and its impact on public health and ecosystem balance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderVibrionales
FamilyVibrionaceae
GenusVibrio
SpeciesVibrio cholerae
Strainstrain TSY216

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Vibrio cholerae strain TSY216
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature20
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Mollusca, Mammalia
Cell arrangementSingles
SporulationNonsporulating
Energy sourceHeterotroph
PathogenicityHuman

Genome Summary

Vibrio cholerae strain TSY216 chromosome 1, complete sequence.

Gene Summary

Adenine Count

795524 bp

Thymine Count

801979 bp

Guanine Count

728715 bp

Cytosine Count

726986 bp

Genome Length

3053204 bp

Protein-coding Genes

2704 genes

Non-Coding Genes

127 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
replication initiator protein rctb domain-containing proteinEN12_RS14175Not AvailablePositive746 - 272275282.5
hypothetical proteinEN12_RS14180Not AvailableNegative2942 - 340317775.1
pa3496 family putative envelope integrity proteinEN12_RS14185Not AvailablePositive3766 - 39637533.86
duf3283 family proteinEN12_RS14190Not AvailablePositive4126 - 43357946.66
yebc/pmpr family dna-binding transcriptional regulatorEN12_RS14195A5F1N4Positive4423 - 514226355.0
nad(p)-dependent oxidoreductaseEN12_RS14200O33730Positive5257 - 613230599.2
methyl-accepting chemotaxis proteinEN12_RS14205Q9I0I6Negative6236 - 789760875.3
hypothetical proteinEN12_RS14210Not AvailablePositive7900 - 80947148.67
yibl family ribosome-associated proteinEN12_RS14215P0ADL0Positive8175 - 853113424.5
hth-type transcriptional regulator maltEN12_RS14220Q9KNF3Negative8598 - 11306103595.0

Displaying genes 1 – 10 of 4898 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

181 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0000848hexanoateC6H11O2Chemical structure of hexanoateNot available
Average115.1503Da
Monoisotopic115.075904596Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da

Displaying 1–10 of 181 metabolites

Health Effects

Health ConditionRelationReference
CholeraCausesPMC10103850
Ear infectionsCausesPMC10103850
Wound infectionsCausesPMC10103850
SepticaemiaCausesPMC10103850
Gastrointestinal infectionsCausesPMC10103850
Necrotizing fasciitisCausesPMC10103850
VibriosisCausesPMC10472736
PneumoniaCausesPMC12801787
GastroenteritisCausesPMC12801787
SinusitisCausesPMC12801787

Displaying health effects 1 – 10 of 38 in total