Chlamydia muridarum str. Nigg

Rod

Kingdom

Pseudomonadati

Phylum

Chlamydiota

Class

Chlamydiia

Order

Chlamydiales

Family

Chlamydiaceae

Genus

Chlamydia

Description

Chlamydia muridarum str. Nigg is a Gram-negative bacterium characterized by its rod shape and the presence of flagella. This organism is notable for having two replicons, which may play a role in its genetic stability and adaptability. It has been identified as a pathogen in various hosts, including Homo sapiens and the rodent Petrachloros mirabilis. The health effects associated with C. muridarum str. Nigg primarily include pulmonary disease and bronchointerstitial pneumonia, indicating its potential impact on respiratory health. The bacterium's ability to infect both humans and a rodent species suggests a versatile ecological niche, which could facilitate its transmission and persistence in different environments. C. muridarum str. Nigg is cataloged under accession numbers NC_002182.1 and NC_002620.2, providing critical genetic information for further studies. The presence of flagella may enhance its motility, potentially influencing its pathogenic mechanisms and interactions with host tissues. Understanding the biology and ecology of Chlamydia muridarum str. Nigg sheds light on the complexities of interspecies transmission of pathogens. The dual host range highlights the importance of studying such organisms in the context of zoonotic diseases, as they may serve as reservoirs for infections that could affect human health.

Taxonomy

KingdomPseudomonadati
PhylumChlamydiota
ClassChlamydiia
OrderChlamydiales
FamilyChlamydiaceae
GenusChlamydia
SpeciesChlamydia muridarum
StrainNigg

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Chlamydia muridarum str. Nigg
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens, Petrachloros mirabilis
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Chlamydia muridarum str. Nigg


Gene Summary

Adenine Count

2468 bp

Thymine Count

2354 bp

Guanine Count

1417 bp

Cytosine Count

1262 bp

Genome Length

7501 bp

Protein-coding Genes

8 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tyrosine-type recombinase/integraseTC_RS04700Not AvailablePositive98 - 101534593.4
site-specific integraseTC_RS04705Not AvailableNegative1064 - 205637767.2
replicative dna helicaseTC_RS04710Not AvailablePositive2154 - 350951493.9
virulence plasmid protein pgp2-dTC_RS04715Not AvailablePositive3503 - 456441329.7
virulence factor pgp3TC_RS04720Not AvailablePositive4631 - 542527667.9
virulence plasmid protein pgp4-dTC_RS04725Not AvailablePositive5494 - 580212011.0
para family proteinTC_RS04730Not AvailablePositive5831 - 662529165.2
ct583 family proteinTC_RS04735Not AvailablePositive6622 - 736228135.7
porphobilinogen synthaseTC_RS00005Not AvailablePositive266 - 126737452.3
na(+)-translocating nadh-quinone reductase subunit aTC_RS00010Not AvailableNegative1300 - 269751591.9

Displaying genes 1 – 10 of 942 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

39 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002751(S)-4-amino-5-oxopentanoateC5H9NO3Chemical structure of (S)-4-amino-5-oxopentanoateNot available
Average131.1299Da
Monoisotopic131.0582432Da
BASm0002812aldehydo-D-glucose 6-phosphateC6H13O9PChemical structure of aldehydo-D-glucose 6-phosphateNot available
Average260.1358Da
Monoisotopic260.0297185Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002833FMNH2C17H21N4O9PChemical structure of FMNH25666-16-0
Average456.3438Da
Monoisotopic456.1046148Da
BASm0002858all-trans-undecaprenyl phosphateC55H89O4PChemical structure of all-trans-undecaprenyl phosphateNot available
Average845.288Da
Monoisotopic844.6509455Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da

Displaying 1–10 of 39 metabolites

Health Effects

Health ConditionRelationReference
Pulmonary diseaseCausesPMC11275779
Bronchointerstitial pneumoniaCausesPMC11275779

Displaying health effects 1 – 2 of 2 in total