Roseburia intestinalis M50/1

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Roseburia

Description

Roseburia intestinalis M50/1 is a Gram-positive, rod-shaped bacterium that thrives in a temperature range of mesophilic to thermophilic environments, belonging to the category of Psychrophiles. It is a Heterotroph, obtaining energy by breaking down organic compounds, specifically complex polysaccharides, in anaerobic conditions. This microbe produces energy through the process of fermentation, wherein it converts organic matter into ATP. The Gram stain reveals a positive reaction, indicating the presence of a thick peptidoglycan layer in the bacterial cell wall. Roseburia intestinalis M50/1 exhibits a rod-shaped morphology, with a typical length of 0.5-1.5 μm and a width of 0.2-0.5 μm. It is found in the intestinal tract of humans and animals, where it plays a crucial role in the breakdown and metabolism of complex carbohydrates. As an Obligate Anaerobe, Roseburia intestinalis M50/1 is highly sensitive to oxygen and requires a strictly anaerobic environment to survive. This is evident in its inability to tolerate even low levels of oxygen, which can inhibit its metabolic processes. Despite being a relatively unknown microbe, Roseburia intestinalis M50/1 has significant implications in human health. Its ability to degrade complex carbohydrates makes it a valuable player in the gut microbiome, contributing to the regulation of blood sugar levels and the prevention of diseases such as diabetes and metabolic syndrome. Furthermore, studies have shown that Roseburia intestinalis M50/1 is capable of producing short-chain fatty acids, which are essential for gut health and immune system function. The unique genetic makeup of this microbe also offers potential insights into the evolution of gut microbiota and the development of novel probiotics. As such, Roseburia intestinalis M50/1 remains an important area of research, offering promising avenues for the understanding and improvement of human health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusRoseburia
SpeciesRoseburia intestinalis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Roseburia intestinalis M50/1
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Roseburia intestinalis M50/1

Accession NumberNC_021040.1

Gene Summary

Adenine Count

1245835 bp

Thymine Count

1092846 bp

Guanine Count

965496 bp

Cytosine Count

756490 bp

Genome Length

4143550 bp

Protein-coding Genes

3799 genes

Non-Coding Genes

95 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Putative transcriptional repressor dicaROI_RS16860Not Available-3659725 - 366014115514.4
hypothetical proteinROI_RS16865Not Available+3660734 - 36609106948.32
Gp68ROI_RS16870Not Available+3660907 - 36610927242.1
Helix-turn-helix transcriptional regulatorROI_RS16875Not Available+3661110 - 36613709548.61
Mu transposase c-terminal domain-containing proteinROI_RS16880Not Available+3661384 - 366347181159.3
Phage transposaseROI_RS16885Not Available+3663511 - 366449437273.3
Lytic tail proteinROI_RS16890Not Available+3664510 - 366513023574.7
hypothetical proteinROI_RS16895Not Available+3665127 - 36653849929.31
Regulatory protein gemaROI_RS16900Not Available+3665377 - 366581116284.8
hypothetical proteinROI_RS16905Not Available+3665786 - 36660439647.72

Displaying genes 1 – 10 of 3894 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

280 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da

Displaying 1–10 of 280 metabolites