Roseburia inulinivorans DSM 16841

Gram-negativeNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Roseburia

Description

Roseburia inulinivorans DSM 16841 is a Gram-positive, rod-shaped bacterium classified as an obligate anaerobe. This organism thrives optimally at mesophilic temperatures, typically ranging between 30°C to 37°C, making it well-suited for the human gut environment. As a heterotroph, Roseburia inulinivorans relies on organic compounds for its energy and growth, specifically fermenting dietary fibers such as inulin, a polysaccharide commonly found in many plants. This bacterium is primarily isolated from the human gastrointestinal tract, where it plays a pivotal role in the fermentation of dietary fibers into short-chain fatty acids (SCFAs), particularly butyrate. Butyrate is significant for colonic health, serving as an energy source for colonocytes and contributing to the maintenance of gut integrity and function. Roseburia inulinivorans can also be found in the fecal microbiota of various populations, highlighting its importance in human health and the gut microbiome's diversity. With its ability to process inulin, Roseburia inulinivorans is often associated with the consumption of prebiotic-rich foods, such as artichokes, garlic, and onions. Its proliferation in the gut is linked to various health benefits, including potential anti-inflammatory properties and modulation of immune responses. Moreover, this microbe's presence is inversely correlated with conditions such as obesity and type 2 diabetes, indicating its role in metabolic health. Overall, Roseburia inulinivorans serves as a crucial player in the gut ecosystem, illustrating the intricate relationship between diet, microbial diversity, and human health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusRoseburia
SpeciesRoseburia inulinivorans
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Roseburia inulinivorans DSM 16841

Accession NumberACFY00000000.1

Gene Summary

Adenine Count

1173957 bp

Thymine Count

1177058 bp

Guanine Count

844636 bp

Cytosine Count

852811 bp

Genome Length

4048462 bp

Protein-coding Genes

4415 genes

Non-Coding Genes

59 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+148 - 262Not Available
crispr-associated endonuclease cas3-hdROSEINA2194_00001Not Available+211 - 78321899.1
crispr-associated helicase cas3ROSEINA2194_00002Not Available+780 - 240562520.8
hypothetical proteinROSEINA2194_00003Not Available+2426 - 25695556.72
crispr-associated protein cas5, dvulg subtypeROSEINA2194_00004Not Available+2587 - 333029005.5
crispr-associated protein, csd1 familyROSEINA2194_00005Not Available+3323 - 524273245.0
hypothetical proteinROSEINA2194_00006Not Available+5242 - 608731533.3
crispr-associated protein cas4ROSEINA2194_00007Not Available+6074 - 675126165.4
Ncrna_class:srp_rnaNot AvailableNot Available+6085 - 6187Not Available
crispr-associated endonuclease cas1, dvulg subtypeROSEINA2194_00008Not Available+6748 - 777939521.1

Displaying genes 1 – 10 of 4474 in total

Pathways

160 pathways

Metabolites

366 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da

Displaying 1–10 of 366 metabolites