Roseburia faecis

Gram-positiveNon-motileanaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Roseburia

Description

Roseburia faecis is a nonsporulating, mesophilic, fermentative bacterium classified within the animal intestinal microflora. As a member of the human gut microbiome, R. faecis plays a crucial role in the digestion of complex polysaccharides, particularly dietary fibers, through its chemoheterotrophic metabolism. This bacterium utilizes a range of organic substrates, contributing to the fermentation process that generates short-chain fatty acids (SCFAs), such as butyrate, which are essential for maintaining gut health and overall metabolic balance. The presence of R. faecis is often associated with a healthy gut environment and has been linked to a variety of beneficial health outcomes, including anti-inflammatory effects and enhanced gut barrier function. It thrives in the intestine, where it contributes to the diverse microbial community that aids in the degradation of nutrients and fortification of host immunity. Interestingly, the abundance of R. faecis in the gut microbiota has been correlated with various dietary patterns, particularly those rich in fiber. This highlights the dynamic relationship between diet and microbial composition; an increase in fiber intakes, such as whole grains and fruits, can foster an environment conducive to the growth of R. faecis, thereby enhancing its therapeutic potential. This illustrates not only the importance of microbial diversity in the gut but also underscores dietary modulation as a strategic approach to promoting gut health and preventing metabolic disorders.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusRoseburia
SpeciesRoseburia faecis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatAnimal Intestinal Microflora
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Roseburia faecis

Accession NumberCVRR00000000.1

Gene Summary

Adenine Count

949772 bp

Thymine Count

952284 bp

Guanine Count

710898 bp

Cytosine Count

721740 bp

Genome Length

3334694 bp

Protein-coding Genes

3168 genes

Non-Coding Genes

55 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
23s ribosomal rnaNot AvailableNot Available+5 - 2890Not Available
16s ribosomal rnaNot AvailableNot Available+45 - 1566Not Available
hypothetical proteinM72_32041Not Available-456 - 6145473.97
diguanylate cyclaseM72_18871Not Available+866 - 204144528.8
hypothetical proteinM72_18881Not Available-2292 - 270814987.7
hypothetical proteinM72_18891Not Available-3146 - 32654700.54
hypothetical proteinM72_18901Not Available-3974 - 436915414.6
hypothetical proteinM72_18911Not Available-4370 - 466311633.2
hypothetical proteinM72_18921Not Available-5038 - 567623949.7
putative metal-binding proteinM72_18931Not Available-5666 - 595311001.1

Displaying genes 1 – 10 of 3223 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

139 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm0000848hexanoateC6H11O2Chemical structure of hexanoateNot available
Average115.1503Da
Monoisotopic115.075904596Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da
BASm0001086scyllo-inososeC6H10O6Chemical structure of scyllo-inososeNot available
Average178.14Da
Monoisotopic178.0477381Da
BASm0001142butanoateC4H7O2Chemical structure of butanoateNot available
Average87.099Da
Monoisotopic87.045153045Da

Displaying 1–10 of 139 metabolites