Staphylococcus aureus

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus aureus is a Gram-positive coccus that typically arranges itself in clusters or singles. This bacterium is non-motile and does not possess flagella, indicating a lack of swimming capability. It exhibits facultative anaerobic growth, allowing it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature classified as mesophilic, favoring conditions around 3.0 °C. S. aureus is primarily host-associated, reflecting its biotic relationship as a free-living organism that can inhabit various host environments, including humans and animals. Its pathogenic potential is well-documented, as it can cause diseases in both animal and human hosts. The organism has a complex genomic architecture, with a total of 48 replicons identified in its genome, accessible through multiple genome accession numbers. The ability of S. aureus to inhabit diverse ecological niches, coupled with its pathogenic traits, underscores its significance in microbiology and medicine. This adaptability may contribute to its prevalence in various infections, highlighting the importance of ongoing research into its genetics and mechanisms of pathogenicity. Understanding S. aureus's ecological relationships and growth requirements is crucial for developing effective treatments and prevention strategies against infections caused by this opportunistic pathogen.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus aureus
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus aureus
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature3
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementClusters - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityAnimal; Human

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Superantigen-encoding pathogenicity island proteinBN1321_180079Not AvailablePositive421623 - 4218478867.24
Hypothetical proteinBN1321_180080Not AvailablePositive421887 - 42233617252.5
Hypothetical proteinBN1321_180081Not AvailablePositive422350 - 4225718453.32
Hypothetical proteinBN1321_180082Not AvailablePositive422819 - 42307910173.2
Hypothetical proteinBN1321_180083Not AvailablePositive423094 - 42357318479.2
Single strand dna binding proteinBN1321_180084Not AvailablePositive423570 - 42421123862.2
Orf033BN1321_180085Q5HJ26Positive424211 - 42463015673.1
Hypothetical proteinBN1321_180086Not AvailablePositive424644 - 42531225837.7
Hnh homing endonucleaseBN1321_180087Not AvailablePositive425312 - 42609130202.6
Orf012BN1321_180088Not AvailablePositive426063 - 42686631927.8

Displaying genes 11 – 20 of 91207 in total

Metabolites

162 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0000848hexanoateC6H11O2Chemical structure of hexanoateNot available
Average115.1503Da
Monoisotopic115.075904596Da

Displaying 1–10 of 162 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionsCausesPMC10127087
Bones and joint infectionsCausesPMC10127087
Infective endocarditisCausesPMC10127087
Cardiovascular disordersCausesPMC10127087
OsteomyelitisCausesPMC10127087
BacteremiaCausesPMC10127087
PneumoniaCausesPMC10127087
Skin and soft tissue infectionsCausesPMC10269700
EndocarditisCausesPMC10269700
PneumoniaCausesPMC10269700

Displaying health effects 1 – 10 of 115 in total