Staphylococcus aureus

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus aureus is a Gram-positive coccus that typically arranges itself in clusters or singles. This bacterium is non-motile and does not possess flagella, indicating a lack of swimming capability. It exhibits facultative anaerobic growth, allowing it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature classified as mesophilic, favoring conditions around 3.0 °C. S. aureus is primarily host-associated, reflecting its biotic relationship as a free-living organism that can inhabit various host environments, including humans and animals. Its pathogenic potential is well-documented, as it can cause diseases in both animal and human hosts. The organism has a complex genomic architecture, with a total of 48 replicons identified in its genome, accessible through multiple genome accession numbers. The ability of S. aureus to inhabit diverse ecological niches, coupled with its pathogenic traits, underscores its significance in microbiology and medicine. This adaptability may contribute to its prevalence in various infections, highlighting the importance of ongoing research into its genetics and mechanisms of pathogenicity. Understanding S. aureus's ecological relationships and growth requirements is crucial for developing effective treatments and prevention strategies against infections caused by this opportunistic pathogen.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus aureus
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus aureus
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature3
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementClusters - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityAnimal; Human

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive404999 - 405010Not Available
Hypothetical proteinBN1321_180070O32163Positive415473 - 41593717017.3
fes cluster formation proteinBN1321_180071Q7A6L4Positive416088 - 41748552534.2
IntegraseBN1321_180072Not AvailableNegative417553 - 41860241744.0
Hypothetical proteinBN1321_180073Not AvailableNegative418664 - 4188768006.85
Gp2BN1321_180074Not AvailableNegative419010 - 4191776169.57
Hypothetical proteinBN1321_180075Not AvailableNegative419181 - 41968119284.0
Phage repressor proteinBN1321_180076Not AvailableNegative419732 - 42037024272.1
Cro-like repressorBN1321_180077Not AvailablePositive420561 - 4208159986.03
Phage anti-repressorBN1321_180078Not AvailablePositive420831 - 42162230174.8

Displaying genes 1 – 10 of 91207 in total

Metabolites

16 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0001691hydrogenselenideHSeChemical structure of hydrogenselenideNot available
Average79.98Da
Monoisotopic80.924896Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0001921(S)-3-methyl-2-oxopentanoateC6H9O3Chemical structure of (S)-3-methyl-2-oxopentanoate1460-34-0
Average129.1339Da
Monoisotopic129.0551692Da
BASm0002282(2R)-2,3-dihydroxy-3-methylbutanoateC5H9O4Chemical structure of (2R)-2,3-dihydroxy-3-methylbutanoateNot available
Average133.1226Da
Monoisotopic133.0500838Da
BASm0002307(2R,3R)-2,3-dihydroxy-3-methylpentanoateC6H11O4Chemical structure of (2R,3R)-2,3-dihydroxy-3-methylpentanoateNot available
Average147.1491Da
Monoisotopic147.06573384Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da
BASm0003187N-succinyl-(2S,6S)-2,6-diaminoheptanedioateC11H16N2O7Chemical structure of N-succinyl-(2S,6S)-2,6-diaminoheptanedioateNot available
Average288.257Da
Monoisotopic288.096848Da

Displaying 1–10 of 16 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionsCausesPMC10127087
Bones and joint infectionsCausesPMC10127087
Infective endocarditisCausesPMC10127087
Cardiovascular disordersCausesPMC10127087
OsteomyelitisCausesPMC10127087
BacteremiaCausesPMC10127087
PneumoniaCausesPMC10127087
Skin and soft tissue infectionsCausesPMC10269700
EndocarditisCausesPMC10269700
PneumoniaCausesPMC10269700

Displaying health effects 1 – 10 of 115 in total