Staphylococcus aureus

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus aureus is a Gram-positive coccus that typically arranges itself in clusters or singles. This bacterium is non-motile and does not possess flagella, indicating a lack of swimming capability. It exhibits facultative anaerobic growth, allowing it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature classified as mesophilic, favoring conditions around 3.0 °C. S. aureus is primarily host-associated, reflecting its biotic relationship as a free-living organism that can inhabit various host environments, including humans and animals. Its pathogenic potential is well-documented, as it can cause diseases in both animal and human hosts. The organism has a complex genomic architecture, with a total of 48 replicons identified in its genome, accessible through multiple genome accession numbers. The ability of S. aureus to inhabit diverse ecological niches, coupled with its pathogenic traits, underscores its significance in microbiology and medicine. This adaptability may contribute to its prevalence in various infections, highlighting the importance of ongoing research into its genetics and mechanisms of pathogenicity. Understanding S. aureus's ecological relationships and growth requirements is crucial for developing effective treatments and prevention strategies against infections caused by this opportunistic pathogen.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus aureus
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus aureus
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature3
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementClusters - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityAnimal; Human

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive404999 - 405010Not Available
Hypothetical proteinBN1321_180070O32163Positive415473 - 41593717017.3
fes cluster formation proteinBN1321_180071Q7A6L4Positive416088 - 41748552534.2
IntegraseBN1321_180072Not AvailableNegative417553 - 41860241744.0
Hypothetical proteinBN1321_180073Not AvailableNegative418664 - 4188768006.85
Gp2BN1321_180074Not AvailableNegative419010 - 4191776169.57
Hypothetical proteinBN1321_180075Not AvailableNegative419181 - 41968119284.0
Phage repressor proteinBN1321_180076Not AvailableNegative419732 - 42037024272.1
Cro-like repressorBN1321_180077Not AvailablePositive420561 - 4208159986.03
Phage anti-repressorBN1321_180078Not AvailablePositive420831 - 42162230174.8

Displaying genes 1 – 10 of 91207 in total

Metabolites

23 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0001358lactateC3H5O3Chemical structure of lactateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da
BASm00033532-dehydro-3-deoxy-6-phospho-D-galactonateC6H8O9PChemical structure of 2-dehydro-3-deoxy-6-phospho-D-galactonate32120-43-7
Average255.0961Da
Monoisotopic254.9905934Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0003983di-trans,octa-cis-undecaprenyl phosphateC55H89O4PChemical structure of di-trans,octa-cis-undecaprenyl phosphateNot available
Average845.288Da
Monoisotopic844.6509455Da
BASm0004066di-trans,octa-cis-undecaprenolC55H90OChemical structure of di-trans,octa-cis-undecaprenolNot available
Average767.324Da
Monoisotopic766.6991675Da

Displaying 1–10 of 23 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionsCausesPMC10127087
Bones and joint infectionsCausesPMC10127087
Infective endocarditisCausesPMC10127087
Cardiovascular disordersCausesPMC10127087
OsteomyelitisCausesPMC10127087
BacteremiaCausesPMC10127087
PneumoniaCausesPMC10127087
Skin and soft tissue infectionsCausesPMC10269700
EndocarditisCausesPMC10269700
PneumoniaCausesPMC10269700

Displaying health effects 1 – 10 of 115 in total