Borrelia hermsii

Gram-negativeMotile

Kingdom

Pseudomonadati

Phylum

Spirochaetota

Class

Spirochaetia

Order

Spirochaetales

Family

Borreliaceae

Genus

Borrelia

Description

Borrelia hermsii is a Gram-negative, motile bacterium characterized by its possession of flagella, which contribute to its motility. This spirochete has a complex genomic structure, containing 17 replicons, indicative of a high level of genetic diversity and adaptability. The genome of B. hermsii is accessible through multiple accession numbers, including NZ_CP014829.1 and NZ_CP014810.1, among others, reflecting its sequenced nature and facilitating further research into its biology and genetics. The motility of B. hermsii is significant, as it allows the bacterium to navigate through host environments, potentially influencing its interactions with host systems. The presence of flagella, specifically, is critical for its characteristic corkscrew-like movement, which is advantageous for colonization and survival in various ecological niches. Understanding B. hermsii's motility and genomic architecture can provide insights into its ecological role and potential responses to environmental stresses. The diversity observed in its genome may also suggest a capacity for rapid adaptation, which could have implications for its resilience in fluctuating environments or host defenses. This adaptability underscores the importance of studying Borrelia species within the context of their ecological interactions and evolutionary dynamics.

Taxonomy

KingdomPseudomonadati
PhylumSpirochaetota
ClassSpirochaetia
OrderSpirochaetales
FamilyBorreliaceae
GenusBorrelia
SpeciesBorrelia hermsii
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Image of Borrelia hermsii
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens, Ornithodoros hermsi, Ixodida
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Gene Summary

Adenine Count

525 bp

Thymine Count

685 bp

Guanine Count

231 bp

Cytosine Count

440 bp

Genome Length

1881 bp

Protein-coding Genes

1 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

17

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinA0V01_RS00175Not AvailableNegative50027 - 5097135974.3
rna pseudouridine synthaseA0V01_RS00180P59838Negative50949 - 5191136978.1
sodium:solute symporter family transporterA0V01_RS00185P44963Negative51916 - 5333753219.3
duf997 family proteinA0V01_RS06655Not AvailableNegative53330 - 535247741.87
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase coabcA0V01_RS00190O51752Positive53583 - 5475843844.1
heat repeat domain-containing proteinA0V01_RS00195Not AvailableNegative54752 - 5617653333.9
murein biosynthesis integral membrane protein murjA0V01_RS00200O51750Negative56173 - 5769657703.6
trna guanosine(34) transglycosylase tgtA0V01_RS00205B2S1F3Negative57689 - 5881642795.4
lptf/lptg family permeaseA0V01_RS00210Not AvailableNegative58835 - 5990241172.9
lptf/lptg family permeaseA0V01_RS00215Not AvailableNegative59899 - 6118850562.5

Displaying genes 381 – 390 of 917 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

28 records
Metabolite IDMetabolite nameStructureCAS number
BASm00005275-oxopentanoateC5H7O3Chemical structure of 5-oxopentanoateNot available
Average115.109Da
Monoisotopic115.040067665Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002833FMNH2C17H21N4O9PChemical structure of FMNH25666-16-0
Average456.3438Da
Monoisotopic456.1046148Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0003419trimethylamineC3H9NChemical structure of trimethylamine75-50-3
Average59.1103Da
Monoisotopic59.07349929Da
BASm00034704-(phosphooxy)-L-threonineC4H8NO7PChemical structure of 4-(phosphooxy)-L-threonineNot available
Average213.083Da
Monoisotopic213.0049358Da

Displaying 1–10 of 28 metabolites

Health Effects

Health ConditionRelationReference
Relapsing feverCausesPMC10956445
Tick-borne relapsing feverCausesPMC9241729
TbrfCausesPMC9241729
Tick-borne relapsing feverCausesPMC10124667
Tick-borne relapsing feverCausesPMC130189

Displaying health effects 1 – 5 of 5 in total