Borrelia hermsii

Gram-negativeMotile

Kingdom

Pseudomonadati

Phylum

Spirochaetota

Class

Spirochaetia

Order

Spirochaetales

Family

Borreliaceae

Genus

Borrelia

Description

Borrelia hermsii is a Gram-negative, motile bacterium characterized by its possession of flagella, which contribute to its motility. This spirochete has a complex genomic structure, containing 17 replicons, indicative of a high level of genetic diversity and adaptability. The genome of B. hermsii is accessible through multiple accession numbers, including NZ_CP014829.1 and NZ_CP014810.1, among others, reflecting its sequenced nature and facilitating further research into its biology and genetics. The motility of B. hermsii is significant, as it allows the bacterium to navigate through host environments, potentially influencing its interactions with host systems. The presence of flagella, specifically, is critical for its characteristic corkscrew-like movement, which is advantageous for colonization and survival in various ecological niches. Understanding B. hermsii's motility and genomic architecture can provide insights into its ecological role and potential responses to environmental stresses. The diversity observed in its genome may also suggest a capacity for rapid adaptation, which could have implications for its resilience in fluctuating environments or host defenses. This adaptability underscores the importance of studying Borrelia species within the context of their ecological interactions and evolutionary dynamics.

Taxonomy

KingdomPseudomonadati
PhylumSpirochaetota
ClassSpirochaetia
OrderSpirochaetales
FamilyBorreliaceae
GenusBorrelia
SpeciesBorrelia hermsii
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Image of Borrelia hermsii
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens, Ornithodoros hermsi, Ixodida
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Gene Summary

Adenine Count

575 bp

Thymine Count

674 bp

Guanine Count

261 bp

Cytosine Count

182 bp

Genome Length

1692 bp

Protein-coding Genes

2 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

17

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinA0V01_RS07255Not AvailableNegative1 - 2087498.75
fad-dependent thymidylate synthaseA0V01_RS05145O50965Negative894 - 173332866.6
p12 family lipoproteinA0V01_RS05150Not AvailableNegative1990 - 288034129.6
vsp/ospc family lipoproteinA0V01_RS05155Q45209Negative3255 - 388421704.1
hypothetical proteinA0V01_RS05160Not AvailablePositive4653 - 518320454.7
chromosome replication/partitioning proteinA0V01_RS05165Not AvailableNegative5745 - 629922015.8
para family proteinA0V01_RS05170Q60283Negative6355 - 711929634.8
duf226 domain-containing proteinA0V01_RS05175Not AvailableNegative7095 - 767023422.8
plasmid maintenance proteinA0V01_RS05180Not AvailableNegative7677 - 861837721.4
hypothetical proteinA0V01_RS05185Not AvailablePositive8845 - 948325143.4

Displaying genes 1 – 10 of 917 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

27 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001142butanoateC4H7O2Chemical structure of butanoateNot available
Average87.099Da
Monoisotopic87.045153045Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001429decanoateC10H19O2Chemical structure of decanoateNot available
Average171.2567Da
Monoisotopic171.138504852Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00025382-(5-oxo-2,5-dihydrofuran-2-ylidene)acetateC6H3O4Chemical structure of 2-(5-oxo-2,5-dihydrofuran-2-ylidene)acetateNot available
Average139.087Da
Monoisotopic139.0036822Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm00027912-oxopropyl-coenzyme MC5H9O4S2Chemical structure of 2-oxopropyl-coenzyme MNot available
Average197.24Da
Monoisotopic196.994774698Da

Displaying 1–10 of 27 metabolites

Health Effects

Health ConditionRelationReference
Relapsing feverCausesPMC10956445
Tick-borne relapsing feverCausesPMC9241729
TbrfCausesPMC9241729
Tick-borne relapsing feverCausesPMC10124667
Tick-borne relapsing feverCausesPMC130189

Displaying health effects 1 – 5 of 5 in total