Borrelia hermsii

Gram-negativeMotile

Kingdom

Pseudomonadati

Phylum

Spirochaetota

Class

Spirochaetia

Order

Spirochaetales

Family

Borreliaceae

Genus

Borrelia

Description

Borrelia hermsii is a Gram-negative, motile bacterium characterized by its possession of flagella, which contribute to its motility. This spirochete has a complex genomic structure, containing 17 replicons, indicative of a high level of genetic diversity and adaptability. The genome of B. hermsii is accessible through multiple accession numbers, including NZ_CP014829.1 and NZ_CP014810.1, among others, reflecting its sequenced nature and facilitating further research into its biology and genetics. The motility of B. hermsii is significant, as it allows the bacterium to navigate through host environments, potentially influencing its interactions with host systems. The presence of flagella, specifically, is critical for its characteristic corkscrew-like movement, which is advantageous for colonization and survival in various ecological niches. Understanding B. hermsii's motility and genomic architecture can provide insights into its ecological role and potential responses to environmental stresses. The diversity observed in its genome may also suggest a capacity for rapid adaptation, which could have implications for its resilience in fluctuating environments or host defenses. This adaptability underscores the importance of studying Borrelia species within the context of their ecological interactions and evolutionary dynamics.

Taxonomy

KingdomPseudomonadati
PhylumSpirochaetota
ClassSpirochaetia
OrderSpirochaetales
FamilyBorreliaceae
GenusBorrelia
SpeciesBorrelia hermsii
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Image of Borrelia hermsii
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens, Ornithodoros hermsi, Ixodida
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Gene Summary

Adenine Count

1577 bp

Thymine Count

1925 bp

Guanine Count

539 bp

Cytosine Count

644 bp

Genome Length

4685 bp

Protein-coding Genes

2 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

17

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinA0V01_RS07255Not AvailableNegative1 - 2087498.75
fad-dependent thymidylate synthaseA0V01_RS05145O50965Negative894 - 173332866.6
p12 family lipoproteinA0V01_RS05150Not AvailableNegative1990 - 288034129.6
vsp/ospc family lipoproteinA0V01_RS05155Q45209Negative3255 - 388421704.1
hypothetical proteinA0V01_RS05160Not AvailablePositive4653 - 518320454.7
chromosome replication/partitioning proteinA0V01_RS05165Not AvailableNegative5745 - 629922015.8
para family proteinA0V01_RS05170Q60283Negative6355 - 711929634.8
duf226 domain-containing proteinA0V01_RS05175Not AvailableNegative7095 - 767023422.8
plasmid maintenance proteinA0V01_RS05180Not AvailableNegative7677 - 861837721.4
hypothetical proteinA0V01_RS05185Not AvailablePositive8845 - 948325143.4

Displaying genes 1 – 10 of 917 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

38 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0001921(S)-3-methyl-2-oxopentanoateC6H9O3Chemical structure of (S)-3-methyl-2-oxopentanoate1460-34-0
Average129.1339Da
Monoisotopic129.0551692Da
BASm0002243S-methyl-5'-thioinosineC11H14N4O4SChemical structure of S-methyl-5'-thioinosineNot available
Average298.32Da
Monoisotopic298.0735761Da
BASm0002282(2R)-2,3-dihydroxy-3-methylbutanoateC5H9O4Chemical structure of (2R)-2,3-dihydroxy-3-methylbutanoateNot available
Average133.1226Da
Monoisotopic133.0500838Da
BASm0002305(S)-2-ethyl-2-hydroxy-3-oxobutanoateC6H9O4Chemical structure of (S)-2-ethyl-2-hydroxy-3-oxobutanoateNot available
Average145.135Da
Monoisotopic145.0506324Da
BASm0002307(2R,3R)-2,3-dihydroxy-3-methylpentanoateC6H11O4Chemical structure of (2R,3R)-2,3-dihydroxy-3-methylpentanoateNot available
Average147.1491Da
Monoisotopic147.06573384Da
BASm0002749ADP-alpha-D-glucoseC16H23N5O15P2Chemical structure of ADP-alpha-D-glucoseNot available
Average587.329Da
Monoisotopic587.0676862Da
BASm0002751(S)-4-amino-5-oxopentanoateC5H9NO3Chemical structure of (S)-4-amino-5-oxopentanoateNot available
Average131.1299Da
Monoisotopic131.0582432Da
BASm0003107S-inosyl-L-homocysteineC14H19N5O6SChemical structure of S-inosyl-L-homocysteineNot available
Average385.396Da
Monoisotopic385.1056041Da

Displaying 1–10 of 38 metabolites

Health Effects

Health ConditionRelationReference
Relapsing feverCausesPMC10956445
Tick-borne relapsing feverCausesPMC9241729
TbrfCausesPMC9241729
Tick-borne relapsing feverCausesPMC10124667
Tick-borne relapsing feverCausesPMC130189

Displaying health effects 1 – 5 of 5 in total