Orientia tsutsugamushi Karp

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Alphaproteobacteria

Order

Rickettsiales

Family

Rickettsiaceae

Genus

Orientia

Description

Orientia tsutsugamushi Karp is a Gram-negative, aerobic bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This pathogen is mesophilic, thriving at moderate temperatures. O. tsutsugamushi Karp possesses two replicons, which are essential for its genetic stability and replication. This organism is primarily known for its free-living biotic relationship, but it notably serves as a pathogen to humans, causing scrub typhus, a disease transmitted by mite vectors. The interaction between O. tsutsugamushi Karp and its human host highlights the significant impact of this bacterium on public health, particularly in endemic regions. Genomic data for O. tsutsugamushi Karp can be referenced through accessions CP094645.1 and LS398548.1, which provide insights into its genetic composition and potential virulence factors. Understanding the traits and behavior of O. tsutsugamushi Karp is crucial for developing strategies to control and prevent scrub typhus, especially in areas where the disease is prevalent. The ecological role of O. tsutsugamushi Karp as a free-living bacterium and its pathogenic relationship with humans underscores the complexity of host-pathogen interactions and the importance of vector control in managing diseases caused by this organism.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassAlphaproteobacteria
OrderRickettsiales
FamilyRickettsiaceae
GenusOrientia
SpeciesOrientia tsutsugamushi
StrainKarp

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Image of Orientia tsutsugamushi Karp
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatNot Available
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Orientia tsutsugamushi Karp, Complete Genome

Gene Summary

Adenine Count

853497 bp

Thymine Count

855674 bp

Guanine Count

377721 bp

Cytosine Count

381814 bp

Genome Length

2468706 bp

Protein-coding Genes

2771 genes

Non-Coding Genes

69 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
conjugative transfer proteinKARP_01430Not AvailableNegative1340855 - 13410256661.08
conjugative transfer proteinKARP_01431Not AvailableNegative1341118 - 13413127601.81
hnh endonucleaseKARP_01432P24200Negative1341522 - 134189914769.0
reverse transcriptaseKARP_01433P19593Negative1342002 - 134323747437.9
conjugal transfer protein traaKARP_01434Q44349Positive1343938 - 1346778107838.0
conjugal transfer protein traiKARP_01435Not AvailablePositive1346897 - 134841456437.9
conjugal transfer protein traiKARP_01436Not AvailablePositive1348428 - 134897920173.2
transposaseKARP_01437B7NGZ6Positive1349031 - 135002638484.6
conjugal transfer proteinKARP_01438P09130Negative1350036 - 135128346686.4
conjugal transfer proteinKARP_01439Not AvailableNegative1351285 - 135179119585.2

Displaying genes 4321 – 4330 of 5470 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Scrub typhusCausesPMC11039911
Scrub typhusCausesPMC13464350
Scrub typhusCausesPMC6005640
Scrub typhusCausesPMC8460164

Displaying health effects 1 – 4 of 4 in total