Orientia tsutsugamushi Karp

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Alphaproteobacteria

Order

Rickettsiales

Family

Rickettsiaceae

Genus

Orientia

Description

Orientia tsutsugamushi Karp is a Gram-negative, aerobic bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This pathogen is mesophilic, thriving at moderate temperatures. O. tsutsugamushi Karp possesses two replicons, which are essential for its genetic stability and replication. This organism is primarily known for its free-living biotic relationship, but it notably serves as a pathogen to humans, causing scrub typhus, a disease transmitted by mite vectors. The interaction between O. tsutsugamushi Karp and its human host highlights the significant impact of this bacterium on public health, particularly in endemic regions. Genomic data for O. tsutsugamushi Karp can be referenced through accessions CP094645.1 and LS398548.1, which provide insights into its genetic composition and potential virulence factors. Understanding the traits and behavior of O. tsutsugamushi Karp is crucial for developing strategies to control and prevent scrub typhus, especially in areas where the disease is prevalent. The ecological role of O. tsutsugamushi Karp as a free-living bacterium and its pathogenic relationship with humans underscores the complexity of host-pathogen interactions and the importance of vector control in managing diseases caused by this organism.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassAlphaproteobacteria
OrderRickettsiales
FamilyRickettsiaceae
GenusOrientia
SpeciesOrientia tsutsugamushi
StrainKarp

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Image of Orientia tsutsugamushi Karp
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatNot Available
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Orientia tsutsugamushi Karp, Complete Genome

Gene Summary

Adenine Count

853497 bp

Thymine Count

855674 bp

Guanine Count

377721 bp

Cytosine Count

381814 bp

Genome Length

2468706 bp

Protein-coding Genes

2771 genes

Non-Coding Genes

69 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
conjugal transfer proteinKARP_00366Not AvailablePositive334909 - 3351819432.48
uncharacterised proteinKARP_00367Not AvailablePositive335310 - 33564812976.4
nadp-dependent oxidoreductaseKARP_00368P40783Negative336625 - 33777042786.5
cytochrome c biogenesis protein ccmeKARP_00369Q9ZCW6Positive338070 - 33846514979.5
uncharacterised proteinKARP_00370Q9ZD57Positive338496 - 33941034883.5
holliday junction resolvase ruvxKARP_00371B3CU37Positive339407 - 33988017483.6
single-stranded-dna-specific exonuclease recjKARP_00372O32044Positive339894 - 34165465007.8
organic solvent abc transporter atp-binding proteinKARP_00373P30769Negative341981 - 34273628045.5
abc transporter permeaseKARP_00374Q4UNC7Negative342765 - 34355628702.9
ribosomal rna small subunit methyltransferase eKARP_00375Q92J59Negative343669 - 34446029792.3

Displaying genes 3281 – 3290 of 5470 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Scrub typhusCausesPMC11039911
Scrub typhusCausesPMC13464350
Scrub typhusCausesPMC6005640
Scrub typhusCausesPMC8460164

Displaying health effects 1 – 4 of 4 in total