Paenibacillus larvae Med-540, 846

RodMotilefacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Paenibacillaceae

Genus

Paenibacillus

Description

Paenibacillus larvae Med-540, 846 is a Gram-positive bacterium primarily associated with the habitats of beehives, including the gut of honeybees (Apis mellifera), hive debris, and the broader Apinae and Anthophila host groups. This organism is a facultative anaerobe, meaning it can grow in both the presence and absence of oxygen, and it exhibits a rod shape along with mobility capabilities. Notably, P. larvae Med-540, 846 is recognized as the causative agent of American foulbrood (AFB), a severe bacterial disease affecting honeybee brood. The disease poses significant risks to bee populations and can lead to devastating impacts on beekeeping operations. The bacterium has been documented in two distinct replicons, with accessions CP019687.1 and CP019651.1 providing genetic information for further research. Understanding the ecological role and pathogenic potential of Paenibacillus larvae Med-540, 846 is crucial for bee health management. The presence of this bacterium in beehives underlines the importance of monitoring and controlling AFB to mitigate its spread and impact on honeybee colonies. This highlights the intricate relationship between microbial inhabitants and the health of bee populations in their natural habitats.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyPaenibacillaceae
GenusPaenibacillus
SpeciesPaenibacillus larvae
StrainMed-540, 846

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceNot Available
Number of membranesNot Available
Image of Paenibacillus larvae Med-540, 846
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsfacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbeehives; gut; hive debris
Biotic relationshipNot Available
Host(s)Apinae, Apis mellifera, Anthophila
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Paenibacillus larvae Med-540, 846, Complete Genome

Gene Summary

Adenine Count

1194178 bp

Thymine Count

1201314 bp

Guanine Count

942061 bp

Cytosine Count

952397 bp

Genome Length

4289950 bp

Protein-coding Genes

3964 genes

Non-Coding Genes

559 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinERICI_04015Not AvailablePositive3740589 - 37408017764.68
hypothetical proteinERICI_04016Not AvailableNegative3741020 - 37412268397.07
glyoxalase-like domain proteinERICI_04017O31535Positive3741394 - 374190919529.9
d-alanyl-d-alanine carboxypeptidase lipoprotein-like proteinERICI_04018O34866Positive3742060 - 374283928357.6
putative peptidaseERICI_04019P9WM22Negative3742746 - 374309912488.1
putative peptidaseERICI_04020P53425Negative3743117 - 374352714159.0
putative acetyltransferaseERICI_04021Q9HL57Negative3743692 - 374421320386.7
antibiotic biosynthesis monooxygenaseERICI_04022Q9K7R6Negative3744592 - 374493613165.6
iron compound abc transporter, atp-binding proteinERICI_04023Q81LM1Negative3745118 - 374591830438.0
iron compound abc transporter, permease proteinERICI_04024Q56992Negative3745893 - 374696938423.8

Displaying genes 8381 – 8390 of 8919 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
American foulbroodCausesPMC10207761
American foulbrood (afb)CausesPMC10207761
American foulbroodCausesPMC12113734
American foulbroodCausesPMC5072193
American foulbrood (afb)CausesPMC5072193
American foulbrood (afb)CausesPMC5415181
American foulbrood (afb)CausesPMC7067210
American foulbroodCausesPMC7067210
Foulbrood diseaseCausesPMC7067210
AfbCausesPMC10539817

Displaying health effects 1 – 10 of 16 in total