Paenibacillus larvae Med-540, 846

RodMotilefacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Paenibacillaceae

Genus

Paenibacillus

Description

Paenibacillus larvae Med-540, 846 is a Gram-positive bacterium primarily associated with the habitats of beehives, including the gut of honeybees (Apis mellifera), hive debris, and the broader Apinae and Anthophila host groups. This organism is a facultative anaerobe, meaning it can grow in both the presence and absence of oxygen, and it exhibits a rod shape along with mobility capabilities. Notably, P. larvae Med-540, 846 is recognized as the causative agent of American foulbrood (AFB), a severe bacterial disease affecting honeybee brood. The disease poses significant risks to bee populations and can lead to devastating impacts on beekeeping operations. The bacterium has been documented in two distinct replicons, with accessions CP019687.1 and CP019651.1 providing genetic information for further research. Understanding the ecological role and pathogenic potential of Paenibacillus larvae Med-540, 846 is crucial for bee health management. The presence of this bacterium in beehives underlines the importance of monitoring and controlling AFB to mitigate its spread and impact on honeybee colonies. This highlights the intricate relationship between microbial inhabitants and the health of bee populations in their natural habitats.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyPaenibacillaceae
GenusPaenibacillus
SpeciesPaenibacillus larvae
StrainMed-540, 846

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceNot Available
Number of membranesNot Available
Image of Paenibacillus larvae Med-540, 846
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsfacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbeehives; gut; hive debris
Biotic relationshipNot Available
Host(s)Apinae, Apis mellifera, Anthophila
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Paenibacillus larvae Med-540, 846, Complete Genome

Gene Summary

Adenine Count

1200645 bp

Thymine Count

1194031 bp

Guanine Count

952150 bp

Cytosine Count

942121 bp

Genome Length

4288947 bp

Protein-coding Genes

3827 genes

Non-Coding Genes

569 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive384329 - 384340Not Available
Site-specific integraseBXP28_02095Q8R890Negative384456 - 38550539572.4
Membrane associated lipoproteinBXP28_02100Not AvailableNegative385675 - 38613918225.8
Helix-turn-helix family domain xre family transcriptional regulatorBXP28_02105P96631Negative386147 - 38645511755.0
Helix-turn-helix family domain xre family transcriptional regulatorBXP28_02110Not AvailablePositive386604 - 3868469232.01
Helix-turn-helix domain transcriptional regulatorBXP28_02115Not AvailablePositive386932 - 3871146976.43
Hypothetical proteinBXP28_02120Not AvailablePositive387120 - 3873328052.82
Hypothetical proteinBXP28_02125Not AvailablePositive387349 - 3876009789.04
Hypothetical proteinBXP28_02130Not AvailablePositive387616 - 3878469263.03
Abrb family transcriptional regulatorBXP28_02135P08874Positive387843 - 38812710499.8

Displaying genes 1 – 10 of 8919 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
American foulbroodCausesPMC10207761
American foulbrood (afb)CausesPMC10207761
American foulbroodCausesPMC12113734
American foulbroodCausesPMC5072193
American foulbrood (afb)CausesPMC5072193
American foulbrood (afb)CausesPMC5415181
American foulbrood (afb)CausesPMC7067210
American foulbroodCausesPMC7067210
Foulbrood diseaseCausesPMC7067210
AfbCausesPMC10539817

Displaying health effects 1 – 10 of 16 in total