Klebsiella pneumoniae strain EuSCAPE_RS007

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS007 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. This strain exhibits diverse cell arrangements, including chains, pairs, and singles, and possesses flagella, which contributes to its mobility. It thrives optimally at 37°C and falls within a mesophilic temperature range. This bacterium is associated with various hosts, including Homo sapiens, Gallus gallus, and multiple other metazoan species, indicating its broad ecological presence. Notably, K. pneumoniae strain EuSCAPE_RS007 is recognized for its pathogenicity in humans, causing a range of serious health effects such as bacteremia, urinary tract infections, pneumonia, and other intra-abdominal infections. These infections can lead to severe conditions like sepsis and neonatal sepsis, underscoring the strain's clinical significance. The presence of this strain in both free-living and host-associated environments suggests its adaptability and potential for opportunistic infections in various hosts. Its ability to infect a wide range of species—from mammals to birds and amphibians—highlights its ecological versatility and potential as a zoonotic pathogen. Understanding the biological behavior and pathogenic mechanisms of K. pneumoniae strain EuSCAPE_RS007 is crucial for developing strategies to manage infections, especially in healthcare settings where such pathogens pose significant risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS007

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS007
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS007 genome assembly,

Gene Summary

Adenine Count

1146446 bp

Thymine Count

1140331 bp

Guanine Count

1533315 bp

Cytosine Count

1519144 bp

Genome Length

5339236 bp

Protein-coding Genes

4916 genes

Non-Coding Genes

193 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive2013836 - 2013847Not Available
IntegraseSAMEA3649813_01913Not AvailablePositive2015070 - 201629646700.5
uncharacterised proteinSAMEA3649813_01914Not AvailablePositive2016389 - 201733036075.8
Transcriptional regulatorSAMEA3649813_01915Not AvailablePositive2017512 - 201779611198.2
RoiSAMEA3649813_01916Not AvailablePositive2017807 - 201858628437.3
uncharacterised proteinSAMEA3649813_01917Not AvailablePositive2018570 - 201930727327.9
uncharacterised proteinSAMEA3649813_01918Not AvailablePositive2019300 - 20194887224.61
uncharacterised proteinSAMEA3649813_01919Not AvailablePositive2019481 - 201979511508.2
uncharacterised proteinSAMEA3649813_01920Not AvailablePositive2019792 - 202016013535.6
uncharacterised proteinSAMEA3649813_01921Not AvailablePositive2020157 - 202052213986.0

Displaying genes 1 – 10 of 5109 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
SbpCausesPMC10556727
MasldCausesPMC12853991
Urinary tract infectionsCausesPMC12788680
SepticemiaCausesPMC12788680
Abdominal infectionsCausesPMC12788680
Bacterial pneumoniaCausesPMC12788680
Catheter-associated urinary tract infectionCausesPMC2900259
CautiCausesPMC2900259
CystitisCausesPMC4353729
PneumoniaCausesPMC6315841

Displaying health effects 41 – 50 of 53 in total