Klebsiella pneumoniae strain EuSCAPE_RS007

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS007 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. This strain exhibits diverse cell arrangements, including chains, pairs, and singles, and possesses flagella, which contributes to its mobility. It thrives optimally at 37°C and falls within a mesophilic temperature range. This bacterium is associated with various hosts, including Homo sapiens, Gallus gallus, and multiple other metazoan species, indicating its broad ecological presence. Notably, K. pneumoniae strain EuSCAPE_RS007 is recognized for its pathogenicity in humans, causing a range of serious health effects such as bacteremia, urinary tract infections, pneumonia, and other intra-abdominal infections. These infections can lead to severe conditions like sepsis and neonatal sepsis, underscoring the strain's clinical significance. The presence of this strain in both free-living and host-associated environments suggests its adaptability and potential for opportunistic infections in various hosts. Its ability to infect a wide range of species—from mammals to birds and amphibians—highlights its ecological versatility and potential as a zoonotic pathogen. Understanding the biological behavior and pathogenic mechanisms of K. pneumoniae strain EuSCAPE_RS007 is crucial for developing strategies to manage infections, especially in healthcare settings where such pathogens pose significant risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS007

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS007
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS007 genome assembly,

Gene Summary

Adenine Count

1146446 bp

Thymine Count

1140331 bp

Guanine Count

1533315 bp

Cytosine Count

1519144 bp

Genome Length

5339236 bp

Protein-coding Genes

4916 genes

Non-Coding Genes

193 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive2013836 - 2013847Not Available
IntegraseSAMEA3649813_01913Not AvailablePositive2015070 - 201629646700.5
uncharacterised proteinSAMEA3649813_01914Not AvailablePositive2016389 - 201733036075.8
Transcriptional regulatorSAMEA3649813_01915Not AvailablePositive2017512 - 201779611198.2
RoiSAMEA3649813_01916Not AvailablePositive2017807 - 201858628437.3
uncharacterised proteinSAMEA3649813_01917Not AvailablePositive2018570 - 201930727327.9
uncharacterised proteinSAMEA3649813_01918Not AvailablePositive2019300 - 20194887224.61
uncharacterised proteinSAMEA3649813_01919Not AvailablePositive2019481 - 201979511508.2
uncharacterised proteinSAMEA3649813_01920Not AvailablePositive2019792 - 202016013535.6
uncharacterised proteinSAMEA3649813_01921Not AvailablePositive2020157 - 202052213986.0

Displaying genes 1 – 10 of 5109 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC13168211
Neonatal sepsisCausesPMC13168211
PneumoniaCausesPMC13253921
Urinary tract infectionsCausesPMC13253921
BacteremiaCausesPMC13253921
Neonatal sepsisCausesPMC13253921
Pyogenic liver abscessCausesPMC13253921
MeningitisCausesPMC13253921
Early onset neonatal sepsisCausesPMC4560869
Pyogenic liver abscessCausesPMC7332619

Displaying health effects 21 – 30 of 53 in total