Shigella flexneri strain 4028STDY6275090

Gram-negativeRodMotileFacultative

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Shigella

Description

Shigella flexneri strain 4028STDY6275090 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, relying on chemoorganotrophic processes for energy. This strain is characterized by its ability to move, facilitated by the presence of flagella, and it typically exists in pairs or singles. With a mesophilic growth profile, its optimal temperature for proliferation is around 37°C. This bacterium is associated with various hosts, primarily Homo sapiens, but also includes other primates and members of the Pteropodidae family. It plays a significant role in human health, as it is known to cause severe gastrointestinal conditions, including shigellosis, dysentery, and pandemic dysentery. The pathogenic nature of S. flexneri strain 4028STDY6275090 highlights its potential to cause bacillary dysentery, leading to significant health issues in affected populations. Shigella flexneri is nonsporulating and possesses a single replicon, indicating its genomic structure is relatively straightforward. Its biotic relationship is considered free-living, which suggests that while it can thrive in association with hosts, it does not rely exclusively on them for survival. An ecological insight into S. flexneri strain 4028STDY6275090 reveals its importance in public health, particularly in areas with inadequate sanitation and hygiene practices. The bacterium's ability to spread rapidly among human populations underscores the need for effective control measures to prevent outbreaks of dysentery and related diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusShigella
SpeciesShigella flexneri
Strainstrain 4028STDY6275090

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Shigella flexneri strain 4028STDY6275090
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Primates, Pteropodidae
Cell arrangementPairs-Singles
SporulationNonsporulating
Energy source Chemoorganotroph
PathogenicityHuman

Genome Summary

Shigella flexneri strain 4028STDY6275090 genome assembly, contig:

Gene Summary

Adenine Count

1157740 bp

Thymine Count

1161476 bp

Guanine Count

1177919 bp

Cytosine Count

1185036 bp

Genome Length

4682558 bp

Protein-coding Genes

4540 genes

Non-Coding Genes

179 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
quinolinate synthetaseSAMEA3710568_01090Not AvailablePositive1062083 - 106312638300.9
protein pnucSAMEA3710568_01091Not AvailablePositive1063164 - 106388326997.8
zinc transporter zitbSAMEA3710568_01092Not AvailableNegative1063880 - 106482134809.7
homeobox proteinSAMEA3710568_01093Not AvailableNegative1064935 - 106531512872.7
phospho-2-dehydro-3-deoxyheptonate aldolaseSAMEA3710568_01094Not AvailablePositive1065631 - 106668338025.7
phosphoglyceromutaseSAMEA3710568_01095Not AvailableNegative1066850 - 106760228557.9
aldose 1-epimeraseSAMEA3710568_01096Not AvailableNegative1067805 - 106884538192.5
galactokinaseSAMEA3710568_01097Not AvailableNegative1068839 - 106998741443.5
galactose-1-phosphate uridylyltransferaseSAMEA3710568_01098Not AvailableNegative1069991 - 107103739571.6
udp-galactose-4-epimeraseSAMEA3710568_01099Not AvailableNegative1071047 - 107206337254.2

Displaying genes 1131 – 1140 of 4719 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
ShigellosisCausesPMC2600399
ShigellosisCausesPMC5109407
ShigellosisCausesPMC5177732
Severe diarrheaCausesPMC8742002
Dysenteric diseaseCausesPMC8742002
ShigellosisCausesPMC8742002
Bacillary dysenteryCausesPMC8742002
Pandemic dysenteryCausesPMC8742002
Bacillary dysenteryCausesPMC4159516
ShigellosisCausesPMC5429569

Displaying health effects 1 – 10 of 10 in total