Bacteroides fragilis strain NCTC9343

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain NCTC9343 is a Gram-negative, rod-shaped bacterium that exists as a free-living organism primarily associated with the human host. It is a chemoorganotroph, deriving energy from organic compounds. This strain is classified as an anaerobe, meaning it thrives in environments devoid of oxygen, a characteristic that is vital for its survival in the human gut, where oxygen levels are low. The bacterium is non-motile, indicating that it does not possess the ability to move independently. However, it does contain flagella, which are typically associated with motility in other bacterial species. NCTC9343 is mesophilic, with an optimal growth temperature of 37°C, aligning with the human body temperature, which further supports its adaptation to the human gastrointestinal environment. Bacteroides fragilis strain NCTC9343 has a complex genomic structure, with three replicons and a double membrane, which is characteristic of Gram-negative bacteria. The strain is associated with various accessions, including UFTH00000000.1, NC_003228.3, and NC_006873.1, indicating its presence in microbial databases for further study. Ecologically, Bacteroides fragilis plays a significant role in the human microbiome, contributing to gut health and influencing host immune responses. Its ability to thrive in anaerobic conditions and utilize organic matter makes it a key player in the degradation of complex carbohydrates, highlighting its importance in nutrient cycling within the human gut ecosystem.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain NCTC9343

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain NCTC9343
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Bacteroides fragilis NCTC 9343 plasmid pBF9343, complete sequence.

Gene Summary

Adenine Count

11492 bp

Thymine Count

13282 bp

Guanine Count

5996 bp

Cytosine Count

5790 bp

Genome Length

36560 bp

Protein-coding Genes

47 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
replication initiation proteinBF9343_RS21375Not AvailablePositive5893 - 705045182.9
plasmid mobilization proteinBF9343_RS21380Not AvailablePositive8217 - 857314102.4
relaxase/mobilization nuclease domain-containing proteinBF9343_RS21385Not AvailablePositive9008 - 1057059977.4
para family proteinBF9343_RS21390Not AvailablePositive10586 - 1120923398.3
hypothetical proteinBF9343_RS21395Not AvailablePositive11268 - 1170216497.8
helix-turn-helix domain-containing proteinBF9343_RS21400Not AvailableNegative12009 - 1239514678.6
type iv secretory system conjugative dna transfer family proteinBF9343_RS21405Not AvailableNegative12388 - 1434374446.6
hypothetical proteinBF9343_RS21410Not AvailableNegative14347 - 145718498.37
hypothetical proteinBF9343_RS21415Not AvailableNegative14745 - 1518816626.7
hypothetical proteinBF9343_RS21420Not AvailableNegative15268 - 1554010373.5

Displaying genes 11 – 20 of 8849 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

109 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm00005275-oxopentanoateC5H7O3Chemical structure of 5-oxopentanoateNot available
Average115.109Da
Monoisotopic115.040067665Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0000976enol-oxaloacetateC4H2O5Chemical structure of enol-oxaloacetateNot available
Average130.056Da
Monoisotopic129.9913203Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da

Displaying 1–10 of 109 metabolites

Health Effects

No health effects information available for this bacterium.