Bacteroides fragilis strain NCTC9343

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain NCTC9343 is a Gram-negative, rod-shaped bacterium that exists as a free-living organism primarily associated with the human host. It is a chemoorganotroph, deriving energy from organic compounds. This strain is classified as an anaerobe, meaning it thrives in environments devoid of oxygen, a characteristic that is vital for its survival in the human gut, where oxygen levels are low. The bacterium is non-motile, indicating that it does not possess the ability to move independently. However, it does contain flagella, which are typically associated with motility in other bacterial species. NCTC9343 is mesophilic, with an optimal growth temperature of 37°C, aligning with the human body temperature, which further supports its adaptation to the human gastrointestinal environment. Bacteroides fragilis strain NCTC9343 has a complex genomic structure, with three replicons and a double membrane, which is characteristic of Gram-negative bacteria. The strain is associated with various accessions, including UFTH00000000.1, NC_003228.3, and NC_006873.1, indicating its presence in microbial databases for further study. Ecologically, Bacteroides fragilis plays a significant role in the human microbiome, contributing to gut health and influencing host immune responses. Its ability to thrive in anaerobic conditions and utilize organic matter makes it a key player in the degradation of complex carbohydrates, highlighting its importance in nutrient cycling within the human gut ecosystem.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain NCTC9343

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain NCTC9343
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Bacteroides fragilis NCTC 9343, complete sequence.

Gene Summary

Adenine Count

1477686 bp

Thymine Count

1479324 bp

Guanine Count

1125395 bp

Cytosine Count

1122735 bp

Genome Length

5205140 bp

Protein-coding Genes

4182 genes

Non-Coding Genes

94 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
recombinase family proteinBF9343_RS21315Not AvailablePositive129 - 72222677.6
ardc family proteinBF9343_RS21320Not AvailablePositive1147 - 215739113.1
hypothetical proteinBF9343_RS21330Not AvailablePositive3264 - 35159608.38
hypothetical proteinBF9343_RS21335Not AvailablePositive3580 - 37988165.83
hypothetical proteinBF9343_RS21340Not AvailablePositive3830 - 416813344.8
hypothetical proteinBF9343_RS21345Not AvailablePositive4193 - 44118491.2
hypothetical proteinBF9343_RS21350Not AvailablePositive4429 - 473711472.7
hypothetical proteinBF9343_RS21355Not AvailablePositive4748 - 49698322.19
hypothetical proteinBF9343_RS21360Not AvailablePositive5045 - 552719302.3
hypothetical proteinBF9343_RS21365Not AvailablePositive5517 - 57298359.06

Displaying genes 1 – 10 of 8849 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

429 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da

Displaying 1–10 of 429 metabolites

Health Effects

No health effects information available for this bacterium.