Klebsiella pneumoniae strain SIKP130 139_NODE_73

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP130 139_NODE_73 is a Gram-negative, rod-shaped bacterium categorized as a facultative anaerobe, thriving in host-associated environments. It possesses flagella, which contribute to its motility, and typically arranges itself in chains, pairs, or singles. As a chemoheterotroph, this strain primarily derives its energy from organic compounds. The optimal growth temperature for SIKP130 is 37°C, situating it within the mesophilic temperature range. It is characterized by having a single replicon and two membranes, which are typical features of Gram-negative bacteria. This strain can establish infections in a variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other metazoans and vertebrates. It is known for its pathogenicity in humans, being associated with a wide range of health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The ability of Klebsiella pneumoniae to cause severe infections highlights its role as a significant opportunistic pathogen. Given its diverse host range and potential to cause serious health complications, the ecological role of Klebsiella pneumoniae strain SIKP130 could be considerable. Its presence in various environments, coupled with its pathogenic potential, suggests that it may play a significant role in human and animal health, particularly in settings where immunocompromised individuals are present. The strain's free-living biotic relationship may also indicate its resilience and ability to survive in diverse ecological niches.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP130 139_NODE_73

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP130 139_NODE_73
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP130 139_NODE_73, whole genome

Gene Summary

Adenine Count

1179896 bp

Thymine Count

1180595 bp

Guanine Count

1583589 bp

Cytosine Count

1576509 bp

Genome Length

5520589 bp

Protein-coding Genes

5093 genes

Non-Coding Genes

364 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinFAR15_12260Not AvailableNegative2467212 - 24673304569.67
Hypothetical proteinFAR15_12265Not AvailableNegative2467327 - 246774915532.6
Putative transcriptional regulatorFAR15_12270Not AvailableNegative2467746 - 246804811206.3
Dna replication proteinFAR15_12275Not AvailableNegative2468045 - 246878227846.6
Dna replication protein oFAR15_12280Not AvailableNegative2468779 - 246974435939.3
AttlNot AvailableNot AvailablePositive2469280 - 2469292Not Available
Transcriptional regulatorFAR15_12285Not AvailableNegative2469804 - 247060129339.8
Cii proteinFAR15_12290Not AvailableNegative2470687 - 24709088101.71
CroFAR15_12295Not AvailableNegative2470948 - 24711667862.5
Prophage repressorFAR15_12300Not AvailablePositive2471275 - 247193424219.2

Displaying genes 1 – 10 of 5457 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total