Neisseria meningitidis strain N133_06

Neisseria meningitidis strain N133_06 is a Gram-negative cocci bacterium known for its association with human hosts, specifically Homo sapiens. This strain exhibits a characteristic arrangement in pairs and lacks mobility, as it does not possess flagella. It is classified as an aerobe, indicating its requirement for oxygen for growth and metabolism. The optimal growth temperature for this strain is around 35°C, which places it within the mesophilic temperature range. N. meningitidis strain N133_06 is notable for its role in various severe health conditions. It is associated with a range of invasive diseases, including meningitis, sepsis, cellulitis, and septicemia. These conditions are collectively referred to as invasive meningococcal disease (IMD), which includes specific manifestations such as meningococcal meningitis and acute bacterial meningitis (ABM). The strain possesses a single replicon and is characterized by two membranes, a feature typical of Gram-negative bacteria. Its biotic relationship is categorized as free-living, suggesting that it can survive outside of host organisms under certain conditions. The presence of this strain in human hosts signifies its potential as a pathogen, highlighting the importance of understanding its ecological niche and pathogenic mechanisms. Given its significant health impacts, continued research into N. meningitidis strain N133_06 is crucial for developing effective prevention and treatment strategies against the diseases it causes.