Neisseria meningitidis strain N207_18

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria meningitidis strain N207_18 is a Gram-negative cocci bacterium that typically resides in pairs. This strain is classified as an aerobe, meaning it requires oxygen for growth, and it operates optimally at a temperature of 35°C, within a mesophilic temperature range. N207_18 possesses a single replicon and is characterized by having two membranes, which is a common trait among Gram-negative bacteria. This strain is non-motile and does not have flagella, indicating that it does not move independently. Despite being capable of free living, N. meningitidis is primarily associated with humans (Homo sapiens) as its host. The bacterium is known to be pathogenic, causing severe health effects such as meningitis, sepsis, cellulitis, septicemia, and invasive meningococcal disease (IMD). The conditions associated with this strain include bacterial meningitis and acute bacterial meningitis, which can have serious implications for human health. Given its pathogenic potential and the variety of diseases it can cause, N. meningitidis strain N207_18 serves as a critical organism for understanding bacterial infections in humans. Its presence in pairs and its specific habitat in human hosts highlight the ecological niche it occupies, where it can thrive and also pose significant health risks. This underscores the importance of monitoring and studying this strain in clinical microbiology to better understand its behavior and impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria meningitidis
Strainstrain N207_18

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria meningitidis strain N207_18
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementPairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Neisseria meningitidis strain N207_18

Gene Summary

Adenine Count

500803 bp

Thymine Count

506662 bp

Guanine Count

545336 bp

Cytosine Count

530497 bp

Genome Length

2091476 bp

Protein-coding Genes

2120 genes

Non-Coding Genes

53 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcriptional regulatorEUA31_00380Not AvailableNegative60754 - 609487026.39
atp phosphoribosyltransferase regulatory subunitEUA31_00385Not AvailablePositive60922 - 6207341738.2
adenylosuccinate synthaseEUA31_00390Not AvailablePositive62171 - 6347546180.8
protease htpxEUA31_00395Not AvailableNegative63863 - 6470230203.8
heat-shock protein htpxEUA31_00400Not AvailableNegative64699 - 648154431.12
adenylate kinaseEUA31_00405Not AvailablePositive64917 - 6556423217.9
orotidine-5'-phosphate decarboxylaseEUA31_00415Not AvailablePositive66089 - 6682926600.2
d-glycero-beta-d-manno-heptose-7-phosphate kinaseEUA31_00420Not AvailablePositive66885 - 6785635000.0
dna (cytosine-5-)-methyltransferaseEUA31_00425Not AvailablePositive67893 - 6912847801.2
hnh endonucleaseEUA31_00430Not AvailablePositive69130 - 7016140961.7

Displaying genes 81 – 90 of 2173 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

103 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da
BASm0001691hydrogenselenideHSeChemical structure of hydrogenselenideNot available
Average79.98Da
Monoisotopic80.924896Da

Displaying 1–10 of 103 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC11116026
Invasive meningococcal disease (imd)CausesPMC12054086
Meningococcal meningitisCausesPMC1538595
Meningococcal septicemiaCausesPMC1538595
Meningococcal diseaseCausesPMC3125835
Bacterial meningitisCausesPMC3943661
Meningococcal diseaseCausesPMC3943661
Bacterial meningitisCausesPMC4364741
Severe sepsisCausesPMC4364741
Acute bacterial meningitisCausesPMC6306750

Displaying health effects 1 – 10 of 32 in total