Neisseria meningitidis strain N61_09

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria meningitidis strain N61_09 is a pathogenic bacterium that is classified as a Gram-negative cocci and is typically found in pairs. It is an aerobic organism and is mesophilic, with an optimal growth temperature of 35°C. This strain possesses two membranes and lacks mobility, as it does not have flagella. N61_09 is primarily associated with humans (Homo sapiens) and is known to cause a range of severe health conditions including meningitis, sepsis, cellulitis, septicemia, and invasive meningococcal disease (IMD). The strain is responsible for various forms of meningococcal disease, which can manifest as bacterial meningitis and acute bacterial meningitis (ABM). Given the significant health effects associated with this bacterium, it is classified as a free-living organism in its ecological niche. The presence of a single replicon indicates a relatively simple genetic structure, which is common in many pathogenic bacteria. The health implications of N. meningitidis strain N61_09 underline its importance in public health, particularly in regard to outbreaks of invasive meningococcal disease. Understanding the traits of this strain can aid in the development of targeted interventions and treatment strategies to combat the diseases it causes. The distinct habitat and biotic relationships of N. meningitidis suggest a complex interaction with its human hosts, highlighting the need for ongoing research into its pathogenic mechanisms and epidemiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria meningitidis
Strainstrain N61_09

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria meningitidis strain N61_09
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementPairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Neisseria meningitidis strain N61_09

Gene Summary

Adenine Count

500248 bp

Thymine Count

504365 bp

Guanine Count

540848 bp

Cytosine Count

534664 bp

Genome Length

2088618 bp

Protein-coding Genes

2069 genes

Non-Coding Genes

53 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cdp-diacylglycerol--serine o-phosphatidyltransferaseEUA36_03940Not AvailablePositive666589 - 66733527912.5
sulfite exporter taue/safe family proteinEUA36_03945Not AvailablePositive667336 - 66814228060.3
50s ribosomal protein l9EUA36_03950Not AvailableNegative669104 - 66955615762.1
30s ribosomal protein s18EUA36_03955Not AvailableNegative669573 - 6698038993.05
primosomal replication protein nEUA36_03960Not AvailableNegative669810 - 67011211623.3
30s ribosomal protein s6EUA36_03965Not AvailableNegative670113 - 67048113935.8
thioredoxin-disulfide reductaseEUA36_03970Not AvailableNegative670637 - 67158733700.1
copper-translocating p-type atpaseEUA36_03975Not AvailablePositive671726 - 67390376732.4
excinuclease abc subunit uvrcEUA36_03980Not AvailablePositive673958 - 67584471071.9
trna (guanosine(46)-n7)-methyltransferase trmbEUA36_03990Not AvailablePositive677647 - 67836327121.3

Displaying genes 721 – 730 of 2122 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC11116026
Invasive meningococcal disease (imd)CausesPMC12054086
Meningococcal meningitisCausesPMC1538595
Meningococcal septicemiaCausesPMC1538595
Meningococcal diseaseCausesPMC3125835
Bacterial meningitisCausesPMC3943661
Meningococcal diseaseCausesPMC3943661
Bacterial meningitisCausesPMC4364741
Severe sepsisCausesPMC4364741
Acute bacterial meningitisCausesPMC6306750

Displaying health effects 1 – 10 of 32 in total