Neisseria meningitidis strain N61_09

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria meningitidis strain N61_09 is a pathogenic bacterium that is classified as a Gram-negative cocci and is typically found in pairs. It is an aerobic organism and is mesophilic, with an optimal growth temperature of 35°C. This strain possesses two membranes and lacks mobility, as it does not have flagella. N61_09 is primarily associated with humans (Homo sapiens) and is known to cause a range of severe health conditions including meningitis, sepsis, cellulitis, septicemia, and invasive meningococcal disease (IMD). The strain is responsible for various forms of meningococcal disease, which can manifest as bacterial meningitis and acute bacterial meningitis (ABM). Given the significant health effects associated with this bacterium, it is classified as a free-living organism in its ecological niche. The presence of a single replicon indicates a relatively simple genetic structure, which is common in many pathogenic bacteria. The health implications of N. meningitidis strain N61_09 underline its importance in public health, particularly in regard to outbreaks of invasive meningococcal disease. Understanding the traits of this strain can aid in the development of targeted interventions and treatment strategies to combat the diseases it causes. The distinct habitat and biotic relationships of N. meningitidis suggest a complex interaction with its human hosts, highlighting the need for ongoing research into its pathogenic mechanisms and epidemiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria meningitidis
Strainstrain N61_09

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria meningitidis strain N61_09
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementPairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Neisseria meningitidis strain N61_09

Gene Summary

Adenine Count

500248 bp

Thymine Count

504365 bp

Guanine Count

540848 bp

Cytosine Count

534664 bp

Genome Length

2088618 bp

Protein-coding Genes

2069 genes

Non-Coding Genes

53 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetate kinaseEUA36_07610Not AvailableNegative1314284 - 131548042398.2
hypothetical proteinEUA36_07615Not AvailablePositive1315831 - 131613011320.4
cbb3-type cytochrome oxidase assembly protein ccosEUA36_07620Not AvailablePositive1316130 - 13163157145.57
mfs transporterEUA36_07625Not AvailablePositive1316305 - 131761547383.3
dna polymerase iii subunit epsilonEUA36_07630Not AvailablePositive1317773 - 131850727004.5
2-c-methyl-d-erythritol 4-phosphate cytidylyltransferaseEUA36_07635Not AvailablePositive1318504 - 131919324604.6
2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthaseEUA36_07640Not AvailablePositive1319225 - 131970717020.6
ribose-5-phosphate isomerase rpiaEUA36_07645Not AvailablePositive1319784 - 132045523921.8
thermonuclease family proteinEUA36_07650Not AvailablePositive1320494 - 132119525959.8
hypothetical proteinEUA36_07655Not AvailablePositive1321211 - 13213907134.02

Displaying genes 1371 – 1380 of 2122 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC11116026
Invasive meningococcal disease (imd)CausesPMC12054086
Meningococcal meningitisCausesPMC1538595
Meningococcal septicemiaCausesPMC1538595
Meningococcal diseaseCausesPMC3125835
Bacterial meningitisCausesPMC3943661
Meningococcal diseaseCausesPMC3943661
Bacterial meningitisCausesPMC4364741
Severe sepsisCausesPMC4364741
Acute bacterial meningitisCausesPMC6306750

Displaying health effects 1 – 10 of 32 in total