Neisseria meningitidis strain N93_11

Neisseria meningitidis strain N93_11 is a Gram-negative bacterium characterized by its cocci shape and arrangement in pairs. This strain is non-motile, lacking flagella, and is classified as an aerobe, indicating that it requires oxygen for growth. N93_11 is mesophilic, with an optimal growth temperature of 35°C, thriving in environments that support moderate temperature ranges. The bacterium is host-associated, primarily found in Homo sapiens, where it can lead to various severe health effects, including meningitis, sepsis, cellulitis, septicemia, and invasive meningococcal disease (IMD). These conditions highlight the pathogen's potential to cause significant morbidity and mortality. N93_11 possesses a single replicon and has a double membrane structure, typical of Gram-negative bacteria, which may contribute to its pathogenicity and ability to evade the host immune responses. As a free-living organism, N93_11's ecological role extends beyond being a mere pathogen; it may participate in complex interactions within human microbiomes. Understanding the specific traits of N93_11 enhances our comprehension of its pathogenic behavior and ecological dynamics, particularly concerning its transmission and the conditions that favor its survival and virulence in human hosts. The accession number for this strain is SDKP00000000.1, which allows for further genetic and genomic exploration of its characteristics.