Neisseria meningitidis strain N101_10

Neisseria meningitidis strain N101_10 is a Gram-negative bacterium characterized by its cocci shape and arrangement in pairs. This strain is an aerobic organism, requiring oxygen for growth, and is classified as mesophilic, with an optimal temperature of 35°C. Notably, N101_10 lacks mobility despite the presence of flagella, indicating that it does not utilize flagellar movement for motility. The bacterium has a single replicon and is surrounded by two membranes, a typical feature of Gram-negative bacteria, which contributes to its structural integrity and protection against environmental stresses. N101_10 is host-associated, primarily residing in Homo sapiens, where it has been implicated in several serious health conditions. These include meningitis, sepsis, cellulitis, septicemia, and invasive meningococcal disease (IMD), among others. The pathogenic potential of N. meningitidis strain N101_10 highlights the ecological dynamics of microbial interactions with human hosts. As a free-living organism, it may play roles in environmental reservoirs that can lead to outbreaks of invasive diseases, particularly in populations susceptible to meningococcal infections. Understanding the traits of this strain is crucial for developing targeted interventions and public health strategies aimed at preventing its associated diseases.