Shigella flexneri strain 551537

Gram-negativeRodMotileFacultative

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Shigella

Description

Shigella flexneri strain 551537 is a pathogenic bacterium primarily associated with human hosts, specifically Homo sapiens, but it is also found in some primates and certain species of bats (Pteropodidae). This gram-negative organism exhibits a rod shape and can be observed in pairs or singles. As a chemoorganotroph, it derives energy from organic compounds, and it has a facultative oxygen requirement, allowing it to thrive in varying oxygen conditions. The strain is motile, possessing flagella, which may contribute to its pathogenic capabilities. It is mesophilic, with an optimal growth temperature of 37°C, aligning with the human body temperature, which facilitates its survival and replication in a host environment. Shigella flexneri strain 551537 has a single replicon and features a double membrane structure, characteristic of gram-negative bacteria. This bacterium is notable for causing severe health effects, including shigellosis, characterized by dysentery and severe diarrhea. It is recognized for its role in pandemic dysentery outbreaks, highlighting its significant public health impact. The nonsporulating nature of this strain indicates that it does not form spores, which may affect its survival strategies outside a host. In summary, Shigella flexneri strain 551537 illustrates the complex ecological relationship between pathogenic bacteria and their hosts, emphasizing the importance of understanding such pathogens in the context of public health and disease prevention.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusShigella
SpeciesShigella flexneri
Strainstrain 551537

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Shigella flexneri strain 551537
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Primates, Pteropodidae
Cell arrangementPairs-Singles
SporulationNonsporulating
Energy source Chemoorganotroph
PathogenicityHuman

Genome Summary

Shigella flexneri strain 551537

Gene Summary

Adenine Count

1080244 bp

Thymine Count

1066209 bp

Guanine Count

1105534 bp

Cytosine Count

1107712 bp

Genome Length

4381487 bp

Protein-coding Genes

4148 genes

Non-Coding Genes

247 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flii/yscn family atpaseDOU91_05330Not AvailablePositive1052510 - 105380247563.1
surface presentation of antigens protein spamDOU91_05335Not AvailablePositive1053895 - 105423313208.3
surface presentation of antigens protein spanDOU91_05340Not AvailablePositive1054220 - 105509832979.5
hypothetical proteinDOU91_05345Not AvailablePositive1055092 - 105597333419.5
escr/yscr/hrcr family type iii secretion system export apparatus proteinDOU91_05350Not AvailablePositive1055978 - 105662824183.0
escs/yscs/hrcs family type iii secretion system export apparatus proteinDOU91_05355Not AvailablePositive1056643 - 10569039444.06
esct/ysct/hrct family type iii secretion system export apparatus proteinDOU91_05360Not AvailablePositive1056903 - 105767328485.5
escu/yscu/hrcu family type iii secretion system export apparatus switch proteinDOU91_05365Not AvailablePositive1057680 - 105870839789.6
hypothetical proteinDOU91_05370Not AvailablePositive1058721 - 10589639085.02
prepilin peptidase-dependent pilinDOU91_05375Not AvailablePositive1059446 - 10597028771.05

Displaying genes 1221 – 1230 of 4396 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

11 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da
BASm0003333(2R)-3-phosphoglycerateC3H4O7PChemical structure of (2R)-3-phosphoglycerateNot available
Average183.033Da
Monoisotopic182.9711102Da
BASm0003346(2R)-2-phosphoglycerateC3H4O7PChemical structure of (2R)-2-phosphoglycerateNot available
Average183.033Da
Monoisotopic182.9711102Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0003491(2S)-2-acetolactateC5H7O4Chemical structure of (2S)-2-acetolactateNot available
Average131.108Da
Monoisotopic131.0349823Da

Displaying 1–10 of 11 metabolites

Health Effects

Health ConditionRelationReference
ShigellosisCausesPMC2600399
ShigellosisCausesPMC5109407
ShigellosisCausesPMC5177732
Severe diarrheaCausesPMC8742002
Dysenteric diseaseCausesPMC8742002
ShigellosisCausesPMC8742002
Bacillary dysenteryCausesPMC8742002
Pandemic dysenteryCausesPMC8742002
Bacillary dysenteryCausesPMC4159516
ShigellosisCausesPMC5429569

Displaying health effects 1 – 10 of 10 in total