Enterococcus faecalis strain EF5473

Enterococcus faecalis strain EF5473 is a Gram-positive, cocci-shaped bacterium that functions as a chemoorganotroph and is classified as a facultative anaerobe. This strain is non-motile and lacks flagella, indicating a stationary lifestyle. It has a single replicon and a single membrane, and it thrives at an optimal temperature of 37°C, placing it within the mesophilic temperature range. EF5473 is known to inhabit multiple environments, contributing to its free-living biotic relationship. This bacterium is associated with a wide range of hosts, including Homo sapiens, various domesticated animals such as Gallus gallus (chickens), Bos (cattle), and Sus scrofa (pigs), as well as aquatic species like Lutjanus russellii (fish) and Danio rerio (zebrafish). It is also found in association with Insecta, Canis lupus familiaris (dogs), Felis catus (cats), and Phocoena phocoena (porpoises). Clinically, Enterococcus faecalis EF5473 is notable for its pathogenicity in humans, being linked to various health issues such as bacteremia, urinary tract infections (UTIs), endocarditis, and meningitis, among others. These infections can occur in multiple body regions, including the urinary tract, intra-abdominal areas, and oral cavity, highlighting its role in nosocomial infections and potential complications during medical procedures. The ecological insight provided by the diverse host range and pathogenic potential of Enterococcus faecalis EF5473 underscores its adaptability and significance in both environmental and clinical settings, reflecting its capacity to thrive in varied habitats while posing health risks to humans and animals alike.