Capnocytophaga canimorsus strain NCTC11921

Gram-negativeRodNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Flavobacteriia

Order

Flavobacteriales

Family

Flavobacteriaceae

Genus

Capnocytophaga

Description

Capnocytophaga canimorsus strain NCTC11921 is a Gram-negative, microaerophilic rod-shaped bacterium that serves as a chemoheterotroph, deriving its energy from organic compounds. This strain is non-motile and has flagella, which may play a role in its environmental interactions. Optimal growth conditions for C. canimorsus occur at 37°C, categorizing it as mesophilic. This bacterium is free-living and has been identified in multiple habitats, indicating a versatile ecological presence. It has been associated with various hosts, including Homo sapiens, Metazoa, Canis lupus familiaris (domestic dog), and Felis catus (domestic cat), suggesting that it may inhabit environments shared with these species. C. canimorsus is clinically significant due to its association with a range of severe health effects in humans. These include bacteremia, endocarditis, meningitis, sepsis, cellulitis, and ocular infections, among others. The bacterium can lead to serious systemic infections and is particularly noted for causing infections following animal bites, particularly from dogs or cats. Understanding the pathogenic potential and ecological relationships of Capnocytophaga canimorsus strain NCTC11921 is essential for public health, especially in contexts involving pet ownership and animal interactions. The bacterium's capability to thrive in diverse environments and its association with various infections highlight its relevance in both clinical and ecological studies.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassFlavobacteriia
OrderFlavobacteriales
FamilyFlavobacteriaceae
GenusCapnocytophaga
SpeciesCapnocytophaga canimorsus
Strainstrain NCTC11921

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Capnocytophaga canimorsus strain NCTC11921
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa, Canis lupus familiaris
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Capnocytophaga canimorsus strain NCTC11921 chromosome 1, complete

Gene Summary

Adenine Count

811190 bp

Thymine Count

804078 bp

Guanine Count

456344 bp

Cytosine Count

456658 bp

Genome Length

2528270 bp

Protein-coding Genes

2219 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional aspartate kinase/homoserine dehydrogenase iEL273_RS05225Not AvailableNegative1183852 - 118626988851.8
alpha/beta fold hydrolaseEL273_RS05230Not AvailableNegative1186281 - 118724636517.0
o-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family proteinEL273_RS05235Not AvailableNegative1187374 - 118864845733.5
nad(p)h-dependent flavin oxidoreductaseEL273_RS05240Not AvailablePositive1189094 - 119004434251.5
Trna-aspNot AvailableNot AvailablePositive1190151 - 1190224Not Available
hypothetical proteinEL273_RS05250Not AvailableNegative1190375 - 119089621109.3
gtpase hflxEL273_RS05255Not AvailablePositive1191006 - 119223247000.5
ykva family proteinEL273_RS05260Not AvailablePositive1192235 - 119265715740.3
aminotransferase class v-fold plp-dependent enzymeEL273_RS05265Not AvailablePositive1192726 - 119394644748.0
lipoprotein signal peptidaseEL273_RS05270Not AvailablePositive1194018 - 119463223139.7

Displaying genes 1051 – 1060 of 2275 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Local wound infectionsCausesPMC10269634
Lethal sepsisCausesPMC10269634
Systemic infectionsCausesPMC10269634
CellulitisCausesPMC10269634
MeningitisCausesPMC10269634
SepsisCausesPMC10269634
BacteremiaCausesPMC10972404
MeningitisCausesPMC10972404
Infective endocarditisCausesPMC10972404
IeCausesPMC10972404

Displaying health effects 1 – 10 of 29 in total