Klebsiella pneumoniae strain NCTC13635

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain NCTC13635 is a Gram-negative, rod-shaped bacterium that exhibits various characteristics crucial for its ecological and pathogenic roles. It is a facultative anaerobe, capable of thriving in both aerobic and anaerobic conditions, and functions as a chemoheterotroph, utilizing organic compounds as energy sources. This strain typically presents in chains, pairs, or as single cells and possesses flagella, allowing for mobility. K. pneumoniae NCTC13635 is known to be mesophilic, with an optimal growth temperature of 37°C, which coincides with human body temperature, underscoring its adaptability to host environments. The strain has one replicon and two membranes, features common to Gram-negative bacteria that contribute to its structural integrity and interaction with host organisms. This bacterium is associated with a range of health effects, particularly in humans, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It has also been implicated in severe conditions such as septicemia and neonatal sepsis. The strain's biotic relationships indicate that it is free-living yet can also infect a variety of hosts, including mammals, birds, and plants. The ability of K. pneumoniae NCTC13635 to inhabit multiple host species and cause significant health issues illustrates its ecological versatility and pathogenic potential. This adaptability may contribute to its persistence in diverse environments, reflecting the complex interactions between microbial pathogens and their hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain NCTC13635

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain NCTC13635
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain NCTC13635


Gene Summary

Adenine Count

1114972 bp

Thymine Count

1116270 bp

Guanine Count

1515447 bp

Cytosine Count

1505944 bp

Genome Length

5252633 bp

Protein-coding Genes

5050 genes

Non-Coding Genes

211 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive390625 - 390639Not Available
IntegraseEL112_RS02025Not AvailablePositive399813 - 40091439916.1
Serine-type dna invertase finEL112_RS02030Not AvailableNegative401013 - 4012518294.86
Serine-type dna invertase finEL112_RS02035Not AvailableNegative401610 - 40207817257.0
Hypothetical proteinEL112_RS02040Not AvailableNegative402120 - 40241911605.3
hypothetical proteinEL112_RS02045Not AvailablePositive402588 - 40297115138.8
Hypothetical proteinEL112_RS02050Not AvailableNegative403289 - 40402325976.2
Tail fiber proteinEL112_RS02055Not AvailableNegative404036 - 40619077743.0
Tail fiber proteinEL112_RS02060Not AvailableNegative406263 - 409358112688.0
Hypothetical proteinEL112_RS02065Not AvailableNegative409355 - 40973514058.0

Displaying genes 1 – 10 of 5261 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 49 in total