Escherichia coli strain PF9285

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain PF9285 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in diverse environments. This strain is capable of mobility due to the presence of flagella and typically exists in pairs or singles. It is mesophilic, with an optimal growth temperature of 37°C, which is consistent with the human body temperature, indicating its adaptation to host-associated habitats. PF9285 interacts with a wide range of hosts, including Homo sapiens, various domestic animals such as Gallus gallus (chickens), Bos taurus (cattle), and Canis lupus familiaris (dogs), as well as plants like Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). This extensive host range suggests ecological versatility and potential for cross-species transmission. In terms of health impacts, E. coli strain PF9285 is associated with numerous infections, including urinary tract infections (UTIs), gastrointestinal diseases, peritonitis, and neonatal meningitis. The strain has been implicated in severe health conditions such as hemolytic uremic syndrome (HUS) and septicemia, highlighting its pathogenic potential in humans and other hosts. The presence of multiple replicons may contribute to its adaptability and resistance mechanisms. The ability of PF9285 to thrive in various host organisms reflects its ecological role as a free-living bacterium, capable of participating in complex microbial communities. Its pathogenicity underscores the importance of monitoring such strains in both clinical and environmental contexts, as they can significantly impact public health and animal welfare.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain PF9285

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain PF9285
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain PF9285


Gene Summary

Adenine Count

1281848 bp

Thymine Count

1289705 bp

Guanine Count

1334188 bp

Cytosine Count

1309821 bp

Genome Length

5215562 bp

Protein-coding Genes

4670 genes

Non-Coding Genes

494 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive65835 - 65847Not Available
AttlNot AvailableNot AvailablePositive74215 - 74226Not Available
AttlNot AvailableNot AvailablePositive80556 - 80570Not Available
Transposase is26E5M00_RS00500Not AvailablePositive80620 - 8132427896.9
RepaE5M00_RS00510Not AvailablePositive81374 - 8209325927.0
replication protein c, incq-typeE5M00_RS00515Not AvailablePositive82080 - 8293131090.6
sulfonamide-resistant dihydropteroate synthase sul2E5M00_RS00525Not AvailablePositive83239 - 8405428529.2
aminoglycoside o-phosphotransferase aph(3'')-ibE5M00_RS00530Not AvailablePositive84115 - 8491829588.2
aminoglycoside o-phosphotransferase aph(6)-idE5M00_RS00535Not AvailablePositive84918 - 8575430825.7
AttrNot AvailableNot AvailablePositive85762 - 85776Not Available

Displaying genes 1 – 10 of 5427 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4786 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4786 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 74 in total