Escherichia coli strain WCHEC025970

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain WCHEC025970 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, which places it within the mesophilic temperature range. It is associated with a wide variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), as well as numerous other vertebrates and invertebrates. The strain has a complex genetic architecture, characterized by six replicons and two membranes, which may contribute to its adaptability and pathogenicity. E. coli WCHEC025970 is known to cause a range of health effects in humans, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis, septicemia, and hemolytic uremic syndrome (HUS). These health implications underscore the strain's role as a significant pathogen in clinical settings. In ecological terms, E. coli WCHEC025970's free-living nature and association with diverse hosts suggest a crucial role in the microbiomes of both humans and animals. Its ability to cause enteric diseases and other infections highlights the importance of monitoring this strain in relation to public health and food safety. The strain's broad host range indicates potential reservoirs in agricultural settings, further emphasizing the need for vigilance in preventing its transmission and managing its health impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain WCHEC025970

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain WCHEC025970
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Gene Summary

Adenine Count

63758 bp

Thymine Count

63963 bp

Guanine Count

55808 bp

Cytosine Count

54729 bp

Genome Length

238258 bp

Protein-coding Genes

249 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

6

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinEYD11_RS26415Not AvailableNegative343 - 5738951.78
hypothetical proteinEYD11_RS26420Not AvailableNegative560 - 104218563.4
incfii family plasmid replication initiator repaEYD11_RS26810Not AvailablePositive1 - 85832679.5
hypothetical proteinEYD11_RS26815Not AvailablePositive1559 - 16994944.99
cpbp family intramembrane glutamic endopeptidaseEYD11_RS24905Not AvailablePositive1797 - 245024308.9
type ii toxin-antitoxin system antitoxin pemiEYD11_RS24910Not AvailablePositive2543 - 28009333.16
type ii toxin-antitoxin system toxin endoribonuclease pemk-mtEYD11_RS24915Not AvailablePositive2802 - 313411881.5
hypothetical proteinEYD11_RS24920Not AvailablePositive3383 - 379814974.9
hypothetical proteinEYD11_RS24925Not AvailableNegative3867 - 437919284.3
is6-like element is26 family transposaseEYD11_RS24930Not AvailableNegative4445 - 514927896.9

Displaying genes 1 – 10 of 567 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total