Escherichia coli strain CRE10

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain CRE10 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It exhibits a cell arrangement characterized by singles and pairs and possesses flagella, indicating motility. The optimal growth temperature for this strain is 37°C, and it thrives in mesophilic conditions, suggesting a preference for moderate temperature ranges. This strain is associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates, such as Apis mellifera and Solanum lycopersicum. The ability to inhabit multiple hosts reflects the strain's ecological versatility and potential for transmission across different species. E. coli CRE10 is known for its pathogenic effects in humans, which include urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemorrhagic colitis. The strain's association with a wide array of health issues, including renal failure and hemolytic uremic syndrome (HUS), underscores its clinical significance. The strain has five replicons and two membranes, indicating a complex genomic structure typical of many E. coli strains. Its free-living biotic relationship suggests that it can exist independently of host organisms, potentially facilitating its spread in various environments. In summary, the ecological and pathogenic characteristics of E. coli strain CRE10 illustrate its adaptability and potential impact on public health, particularly concerning its role as a pathogen in both human and animal hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain CRE10

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain CRE10
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain CRE10 plasmid pCRE10.3, complete sequence.

Gene Summary

Adenine Count

16836 bp

Thymine Count

18666 bp

Guanine Count

13442 bp

Cytosine Count

12740 bp

Genome Length

61684 bp

Protein-coding Genes

77 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellar biosynthesis protein flhaEJC75_RS08190Not AvailableNegative1285364 - 128744274861.7
flagellar biosynthesis protein flhbEJC75_RS08195Not AvailableNegative1287435 - 128858342256.4
protein phosphatase chezEJC75_RS08200Not AvailableNegative1288785 - 128942923977.4
chemotaxis response regulator cheyEJC75_RS08205Not AvailableNegative1289440 - 128982914098.2
protein-glutamate methylesterase/protein glutamine deamidaseEJC75_RS08210Not AvailableNegative1289844 - 129089337443.1
protein-glutamate o-methyltransferase cherEJC75_RS08215Not AvailableNegative1290896 - 129175632864.3
methyl-accepting chemotaxis protein ivEJC75_RS08220Not AvailableNegative1291775 - 129337657573.3
methyl-accepting chemotaxis protein iiEJC75_RS08225Not AvailableNegative1293422 - 129508359947.1
chemotaxis protein chewEJC75_RS08230Not AvailableNegative1295228 - 129573118084.9
chemotaxis protein cheaEJC75_RS08235Not AvailableNegative1295752 - 129771671360.6

Displaying genes 1751 – 1760 of 5176 in total

Metabolites

4812 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4812 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total