Escherichia coli strain AR_0067

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain AR_0067 is a Gram-negative, rod-shaped bacterium that demonstrates facultative anaerobic metabolism and exhibits mobility due to the presence of flagella. It is primarily found in host-associated habitats, indicating its adaptation to living within various organisms. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. This strain has a complex biotic relationship, being free-living yet associated with a diverse array of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and other mammals, birds, and even plants like Solanum lycopersicum (tomato). Such a broad host range may contribute to its ecological versatility and potential for transmission across species. E. coli AR_0067 is notable for its pathogenicity in humans, linked to a variety of health issues including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). These health effects highlight the strain's role in both clinical and environmental contexts, emphasizing its relevance in public health. Moreover, the presence of multiple replicons within its genetic structure suggests a potential for genetic adaptability, which may enhance its ability to survive and proliferate in various environments and hosts. Understanding the pathogenic traits and ecological relationships of E. coli strain AR_0067 is crucial for addressing its impact on health, particularly in terms of preventing and managing infections it may cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain AR_0067

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain AR_0067
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain AR_0067


Gene Summary

Adenine Count

19592 bp

Thymine Count

21465 bp

Guanine Count

24230 bp

Cytosine Count

22136 bp

Genome Length

87423 bp

Protein-coding Genes

96 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative zinc-containing alcohol dehydrogenase superfamily proteinAM446_RS10255Not AvailablePositive1701635 - 170267537406.4
Putative deor transcriptional regulator ygbiAM446_RS10260Not AvailablePositive1702781 - 170355427728.6
lipid kinase yegsAM446_RS10265Not AvailableNegative1703636 - 170453532089.7
protein yegrAM446_RS10270Not AvailablePositive1704950 - 170526711379.8
AttlNot AvailableNot AvailablePositive1705379 - 1705392Not Available
IntegraseAM446_RS10280Not AvailableNegative1705544 - 170655738304.2
Xre family transcriptional regulatorAM446_RS10285Not AvailableNegative1706673 - 170697211047.1
Regulatory proteinAM446_RS10290Not AvailablePositive1707094 - 170736910344.6
Hypothetical proteinAM446_RS28540Not AvailablePositive1707380 - 17075506490.14
GpbAM446_RS10295Not AvailablePositive1707547 - 170804720098.3

Displaying genes 1 – 10 of 5175 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total