Escherichia coli strain UK_Dog_Liverpool

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain UK_Dog_Liverpool is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. It typically resides in host-associated habitats and has an optimal growth temperature of 37°C, categorizing it as mesophilic. This strain has a complex genetic structure with four replicons and possesses two membranes. E. coli UK_Dog_Liverpool is notably associated with a wide range of hosts, including Homo sapiens, various mammals (such as Bos taurus and Canis lupus familiaris), and even certain plants like Solanum lycopersicum. This diverse host range indicates its adaptability and potential ecological impact. Health effects linked to this strain are significant and varied, as it is associated with numerous infections and conditions. These include urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as septicemia and hemolytic uremic syndrome (HUS). The breadth of diseases caused by this strain underscores its pathogenicity in humans and other animals. The diverse interactions of E. coli UK_Dog_Liverpool with multiple hosts suggest its role in the microbiome and its potential implications for both health and disease dynamics. Understanding the pathogenic mechanisms and ecological relationships of this strain can be crucial for managing infections and studying microbial ecology in various environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain UK_Dog_Liverpool

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain UK_Dog_Liverpool
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain UK_Dog_Liverpool chromosome, complete

Gene Summary

Adenine Count

1199086 bp

Thymine Count

1202340 bp

Guanine Count

1237559 bp

Cytosine Count

1230497 bp

Genome Length

4869482 bp

Protein-coding Genes

4500 genes

Non-Coding Genes

253 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
relaxase accessory protein mobcDL545_RS26775Not AvailablePositive1554 - 18089503.72
replication initiation proteinDL545_RS26785Not AvailablePositive2342 - 304327122.7
Is3 family transposaseDL545_RS06665Not AvailablePositive1247146 - 12473708196.78
AttlNot AvailableNot AvailablePositive1248327 - 1248338Not Available
parb/repb/spo0j family partition proteinDL545_RS06670Not AvailableNegative1248486 - 124938233868.4
Parb-like nuclease domain proteinDL545_RS06675Not AvailableNegative1249379 - 125027534064.5
Site-specific recombinaseDL545_RS06680Not AvailableNegative1250265 - 125182160385.6
AttrNot AvailableNot AvailablePositive1251998 - 1252009Not Available
Integrase-like proteinDL545_RS06685Not AvailableNegative1252104 - 125333346644.8
AttlNot AvailableNot AvailablePositive1253499 - 1253526Not Available

Displaying genes 1 – 10 of 4831 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total