Escherichia coli strain 51008369SK1

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 51008369SK1 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both the presence and absence of oxygen. This strain is motile, possessing flagella, and typically resides in host-associated habitats, suggesting a close relationship with various organisms. It can be found in pairs or singles and is mesophilic, with an optimal growth temperature of 37°C. Strain 51008369SK1 has been associated with numerous hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other mammals, birds, and even invertebrates like Apis mellifera and Acanthamoeba castellanii. This diverse host range indicates its adaptability and potential for transmission across different species. The strain is notable for its pathogenicity in humans, causing a range of health effects such as urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions like neonatal meningitis, septicemia, and hemolytic uremic syndrome. These health impacts highlight the strain's role in both community-acquired and nosocomial infections, underscoring its significance in public health. With five replicons and a double membrane structure, Escherichia coli strain 51008369SK1 exemplifies the complexity of bacterial genetics and physiology. Its ability to cause various diseases in multiple hosts not only emphasizes its pathogenic potential but also reflects the intricate interactions within ecosystems, where such bacteria can influence health outcomes across diverse species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 51008369SK1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 51008369SK1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 51008369SK1 plasmid p51008369SK1_A,

Gene Summary

Adenine Count

17294 bp

Thymine Count

17672 bp

Guanine Count

17173 bp

Cytosine Count

19579 bp

Genome Length

71718 bp

Protein-coding Genes

93 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinDNQ41_RS26095Not AvailablePositive1057 - 146115122.6
duf2726 domain-containing proteinDNQ41_RS26100Not AvailablePositive1597 - 212420149.1
hypothetical proteinDNQ41_RS28645Not AvailableNegative2431 - 26468002.39
hypothetical proteinDNQ41_RS26115Not AvailableNegative2696 - 29479549.77
hypothetical proteinDNQ41_RS26120Not AvailableNegative2984 - 328611095.4
division plane positioning atpase mipzDNQ41_RS26125Not AvailableNegative3452 - 411124310.4
tyrosine-type recombinase/integraseDNQ41_RS26130Not AvailableNegative4216 - 504031253.9
hypothetical proteinDNQ41_RS28355Not AvailableNegative5125 - 551414504.5
hypothetical proteinDNQ41_RS26140Not AvailableNegative5597 - 625324420.3
h-ns family nucleoid-associated regulatory proteinDNQ41_RS26145Not AvailableNegative6357 - 682117939.5

Displaying genes 1 – 10 of 5078 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total