Escherichia coli strain AR_0085

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain AR_0085 is a Gram-negative, rod-shaped bacterium that displays a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. This strain is motile, possessing flagella, and typically arranges itself in singles or pairs. It is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, indicating its adaptation to host-associated habitats. E. coli AR_0085 is known to have a wide range of hosts, including Homo sapiens, various mammals (e.g., Bos taurus, Sus scrofa), avian species (e.g., Gallus gallus, Meleagris gallopavo), and even some plants (e.g., Solanum lycopersicum). This extensive host range underscores its ecological versatility and potential for transmission across different species. The strain is implicated in numerous health issues, particularly in humans, where it is associated with urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). Its pathogenicity is evident in its ability to cause diverse clinical manifestations, including diarrhea, septicemia, and colibacillosis. The presence of two replicons and two membranes indicates a complex genetic structure typical of many E. coli strains. Given its pathogenic potential and ability to inhabit a broad range of hosts, E. coli strain AR_0085 highlights the importance of understanding microbial interactions within ecosystems and the potential health risks posed by zoonotic transmission.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain AR_0085

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain AR_0085
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain AR_0085 chromosome, complete genome.

Gene Summary

Adenine Count

1288202 bp

Thymine Count

1284559 bp

Guanine Count

1314856 bp

Cytosine Count

1325435 bp

Genome Length

5213052 bp

Protein-coding Genes

4663 genes

Non-Coding Genes

523 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
d-hexose-6-phosphate mutarotaseAM464_RS26855Not AvailablePositive5141823 - 514270732700.9
methylglyoxal reductase yeaeAM464_RS26860Not AvailableNegative5142755 - 514360931018.4
scaffolding protein mipaAM464_RS26865Not AvailableNegative5143699 - 514444527832.4
protein kinase yeagAM464_RS26870Not AvailablePositive5144881 - 514681574484.3
yeah/yhbh family proteinAM464_RS26875Not AvailablePositive5146928 - 514821149453.2
ggdef domain-containing proteinAM464_RS26880Not AvailablePositive5148358 - 514983356072.6
diguanylate cyclase dgcjAM464_RS26885Not AvailablePositive5150014 - 515150456589.8
mischarged aminoacyl-trna deacylaseAM464_RS26890Not AvailablePositive5151547 - 515205017850.7
small membrane protein yoaiAM464_RS26895Not AvailableNegative5152051 - 51521553771.77
duf441 domain-containing proteinAM464_RS26900Not AvailablePositive5152325 - 515277115256.6

Displaying genes 5111 – 5120 of 5327 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total