Escherichia coli strain 14EC033

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 14EC033 is a Gram-negative, rod-shaped bacterium that exhibits mobility through the presence of flagella. This strain is classified as a facultative anaerobe, enabling it to thrive in both oxygen-rich and oxygen-poor environments. It is typically found in a host-associated habitat but can also exist freely in various ecological niches. The optimal growth temperature for 14EC033 is 37°C, placing it within the mesophilic temperature range. The strain has a complex relationship with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other mammals, birds, and even plants such as Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). This diverse host range indicates its adaptability and potential for cross-species interactions. Strain 14EC033 is associated with numerous health effects, particularly in humans, where it can cause conditions such as urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis, among others. Its pathogenicity is significant, as it can lead to severe outcomes like hemolytic uremic syndrome (HUS) and septicemia. The presence of multiple replicons (seven) and membranes (two) in its structure may contribute to its genetic diversity and resilience in various environments. This adaptability could facilitate its survival and pathogenicity in diverse ecological contexts, highlighting the importance of monitoring such strains in both human health and environmental settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 14EC033

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 14EC033
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Gene Summary

Adenine Count

1140669 bp

Thymine Count

1140359 bp

Guanine Count

1178367 bp

Cytosine Count

1180059 bp

Genome Length

4639454 bp

Protein-coding Genes

4299 genes

Non-Coding Genes

216 genes

# of Chromosomes/Plasmids

7

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
plasmid replication initiator repaCR539_RS24070Not AvailableNegative14 - 104239855.1
caif/grla family transcriptional regulatorCR539_RS24075Not AvailablePositive2182 - 263417576.3
duf1187 family proteinCR539_RS24080Not AvailablePositive2627 - 28427967.46
hypothetical proteinCR539_RS28265Not AvailablePositive2835 - 30116564.31
spfh domain-containing proteinCR539_RS24085Not AvailablePositive3038 - 399134943.4
nfed family proteinCR539_RS24095Not AvailablePositive4371 - 481416405.2
hypothetical proteinCR539_RS24100Not AvailablePositive4999 - 565223548.4
hypothetical proteinCR539_RS24105Not AvailablePositive5686 - 59439730.18
hypothetical proteinCR539_RS24110Not AvailablePositive5924 - 622611311.1
hypothetical proteinCR539_RS24115Not AvailablePositive6223 - 64809620.51

Displaying genes 1 – 10 of 5090 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 74 in total